Western Blot (WB)
(Western blot analysis of SAMHD1 (phospho Thr592) in 293 cells transfected with (A) empty expression vector, (B) wild-type SAMHD1, (C) SAMHD1 (T592A) and (D) SAMHD1 (T592E) with SAMHD1 (phospho Thr592) antibody at 1 μg/ml.)
Rabbit anti-Human, Mouse SAMHD1 Polyclonal Antibody | anti-SAMHD1 antibody
SAMHD1 (phospho Thr592) Antibody
Immunohistochemistry starting at 2.5 mug/mL.
Immunofluorescence start at 20 mug/mL.
Western Blot (WB)
(Western blot analysis of SAMHD1 (phospho Thr592) in 293 cells transfected with (A) empty expression vector, (B) wild-type SAMHD1, (C) SAMHD1 (T592A) and (D) SAMHD1 (T592E) with SAMHD1 (phospho Thr592) antibody at 1 μg/ml.)
Western Blot (WB)
(Western blot analysis of SAMHD1 (phospho Thr592) in 293 cells transfected with (A) empty expression vector, (B) wild-type SAMHD1, (C) SAMHD1 (T592A) and (D) SAMHD1 (T592E) with SAMHD1 (phospho Thr592) antibody at 1 μg/ml.)
Immunohistochemistry (IHC)
(Immunohistochemistry of SAMHD1 (phospho Thr592) in human brain tissue with SAMHD1 (phospho Thr592) antibody at 2.5 μg/ml.)
Immunohistochemistry (IHC)
(Immunohistochemistry of SAMHD1 (phospho Thr592) in human brain tissue with SAMHD1 (phospho Thr592) antibody at 2.5 μg/ml.)
Immunofluorescence (IF)
(Immunofluorescence of phosphoSAMHD1 in human brain tissue with phosphoSAMHD1 antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of phosphoSAMHD1 in human brain tissue with phosphoSAMHD1 antibody at 20 μg/mL.)
NCBI and Uniprot Product Information
NCBI Description
This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]
Uniprot Description
SAMHD1: a protein induced by interferon gamma.
Protein type: EC 3.1.4.-
Chromosomal Location of Human Ortholog: 20q11.23
Cellular Component: nucleoplasm; nucleus; plasma membrane
Molecular Function: dGTP binding; dGTPase activity; nucleic acid binding; protein binding; ribonuclease activity; RNA binding; triphosphoric monoester hydrolase activity; zinc ion binding
Biological Process: dATP catabolic process; defense response to virus; deoxyribonucleotide catabolic process; dGTP catabolic process; protein homotetramerization; regulation of innate immune response
Disease: Aicardi-goutieres Syndrome 5; Chilblain Lupus 2
Research Articles on SAMHD1
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Product Notes
The SAMHD1 samhd1 (Catalog #AAA154446) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SAMHD1 (phospho Thr592) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SAMHD1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Western blot at at 0.5 - 1 mug/ml. Immunohistochemistry starting at 2.5 mug/mL. Immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the SAMHD1 samhd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SAMHD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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