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Immunohistochemistry (IHC) (Human Skin, Epidermis: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit anti-Human SAHH/AHCY Polyclonal Antibody | anti-SAHH/AHCY antibody

Anti-SAHH/AHCY Antibody (aa2-432)

Gene Names
AHCY; SAHH; adoHcyase
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Caprylic acid and ammonium sulfate precipitation
Synonyms
SAHH/AHCY; Polyclonal Antibody; Anti-SAHH/AHCY Antibody (aa2-432); Rabbit Polyclonal to Human SAHH/AHCY; AHCY; Adenosylhomocysteinase; AdoHcyase; SAHH; anti-SAHH/AHCY antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human SAHH/AHCY
Purity/Purification
Caprylic acid and ammonium sulfate precipitation
Form/Format
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Sequence Length
432
Applicable Applications for anti-SAHH/AHCY antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin
Application Notes
IHC-P: 10 ug/ml
Immunogen
Recombinant human Adenosylhomocysteinase protein.
Conjugation
Unconjugated
Epitope
aa2-432
Preparation and Storage
Aliquot and store at -20 degree C or -80 degree C. Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Human Skin, Epidermis: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Skin, Epidermis: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-SAHH/AHCY antibody
S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinasefamily. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine(AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, itregulates the intracellular S-adenosylhomocysteine (SAH) concentrationthought to be important for transmethylation reactions. Deficiency inthis protein is one of the different causes of hypermethioninemia.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
191
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,659 Da
NCBI Official Full Name
adenosylhomocysteinase isoform 1
NCBI Official Synonym Full Names
adenosylhomocysteinase
NCBI Official Symbol
AHCY
NCBI Official Synonym Symbols
SAHH; adoHcyase
NCBI Protein Information
adenosylhomocysteinase
UniProt Protein Name
Adenosylhomocysteinase
UniProt Gene Name
AHCY
UniProt Synonym Gene Names
SAHH; AdoHcyase

NCBI Description

S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Uniprot Description

Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.

Research Articles on SAHH/AHCY

Similar Products

Product Notes

The SAHH/AHCY ahcy (Catalog #AAA2401848) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SAHH/AHCY Antibody (aa2-432) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SAHH/AHCY can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin. IHC-P: 10 ug/ml. Researchers should empirically determine the suitability of the SAHH/AHCY ahcy for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SAHH/AHCY, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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