Western Blot (WB)
(S35B2 Antibody (C-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the S35B2 antibody detected the S35B2 protein (arrow).)
Rabbit anti-Human S35B2 Polyclonal Antibody | anti-SLC35B2 antibody
S35B2 Antibody (C-term)
Western Blot (WB)
(S35B2 Antibody (C-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the S35B2 antibody detected the S35B2 protein (arrow).)
Western Blot (WB)
(S35B2 Antibody (C-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the S35B2 antibody detected the S35B2 protein (arrow).)
Immunohistochemistry (IHC)
(S35B2 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the S35B2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(S35B2 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the S35B2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
Sulfotransferases (e.g., SULT4A1; MIM 608359) use an activated form of sulfate, 3-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS), as a common sulfate donor for sulfation of glycoproteins, proteoglycans, and glycolipids in the endoplasmic reticulum and Golgi apparatus. SLC35B2 is located in the microsomal membrane and transports PAPS from the cytosol, where it is synthesized, into the Golgi lumen (Kamiyama et al., 2003 [PubMed 12716889]).[supplied by OMIM, Mar 2008]
Uniprot Description
SLC35B2: Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. May indirectly participate in activation of the NF- kappa-B and MAPK pathways. Belongs to the nucleotide-sugar transporter family. SLC35B subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 6p21.1
Cellular Component: Golgi membrane; Golgi apparatus; membrane; integral to membrane
Molecular Function: signal transducer activity; 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity
Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; glycosaminoglycan metabolic process; xenobiotic metabolic process; carbohydrate metabolic process; 3'-phosphoadenosine 5'-phosphosulfate transport; pathogenesis; signal transduction; transmembrane transport; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process
Research Articles on SLC35B2
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Product Notes
The SLC35B2 slc35b2 (Catalog #AAA9214179) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 393-421. The S35B2 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's S35B2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the SLC35B2 slc35b2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "S35B2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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