Western Blot (WB)
(Mouse Ryk Antibody (Center) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the Ryk antibody detected the Ryk protein (arrow).)
Rabbit anti-Human, mouse Ryk Polyclonal Antibody | anti-Ryk antibody
Mouse Ryk Antibody (Center)
Western Blot (WB)
(Mouse Ryk Antibody (Center) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the Ryk antibody detected the Ryk protein (arrow).)
Western Blot (WB)
(Mouse Ryk Antibody (Center) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the Ryk antibody detected the Ryk protein (arrow).)
Lyu, J., et al. Dev. Cell 15(5):773-780(2008)
Tamplin, O.J., et al. BMC Genomics 9, 511 (2008) :
Keeble, T.R., et al. J. Neurosci. 26(21):5840-5848(2006)
Schmitt, A.M., et al. Nature 439(7072):31-37(2006)
NCBI and Uniprot Product Information
Uniprot Description
RYK: a receptor tyrosine kinase of the Ryk family. Associates with, and may modulate the signaling of, EphB2 and EphB3. Expressed in nestin-positive progenitor cells and neurons, some oligodendrocytes, O-2A progenitor cells, and type-2 astrocytes in developing CNS.
Protein type: Protein kinase, TK; Kinase, protein; EC 2.7.10.1; Protein kinase, tyrosine (receptor); Membrane protein, integral; TK group; Ryk family
Cellular Component: membrane; cytoplasm; integral to membrane; plasma membrane; nucleus
Molecular Function: transferase activity; Wnt-protein binding; Wnt receptor activity; protein binding; transmembrane receptor activity; frizzled binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; transmembrane receptor protein tyrosine kinase activity; ATP binding; protein kinase activity
Biological Process: axon guidance; Wnt receptor signaling pathway; negative chemotaxis; negative regulation of axon extension involved in axon guidance; signal transduction; protein amino acid phosphorylation; corpus callosum development; neuron differentiation; axonogenesis; positive regulation of MAPKKK cascade; skeletal morphogenesis; phosphorylation; neurite development
Research Articles on Ryk
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Product Notes
The Ryk ryk (Catalog #AAA9210089) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 321-348. The Mouse Ryk Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Ryk can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Ryk ryk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ryk, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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