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Western Blot (WB) (Western blot analysis RSK3 (Phospho-Ser360) using EGF treated Jurkat whole cell lysates)

Rabbit anti-Human, Mouse RSK3 Polyclonal Antibody | anti-RSK3 antibody

RSK3 (Phospho-Ser360) Antibody

Gene Names
RPS6KA2; RSK; HU-2; RSK3; p90RSK2; p90-RSK3; pp90RSK3; MAPKAPK1C; S6K-alpha; S6K-alpha2
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Synonyms
RSK3; Polyclonal Antibody; RSK3 (Phospho-Ser360) Antibody; RPS6KA2; HU-2; MAPKAPK-1c; MAPKAPK1C; p90 ribosomal s6 kinase 3; p90RSK2; Pp90RSK3; Ribosomal S6 kinase 3; RSK-3; S6K-alpha; p90-RSK3; RSK; S6K-alpha-2; S6K-alpha2; MAPKAP kinase 1c; p90-RSK 2; anti-RSK3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
RSK3 (Phospho-Ser360) Antibody detects endogenous levels of RSK3 only when phosphorylated at Ser360
Purity/Purification
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
741
Applicable Applications for anti-RSK3 antibody
Western Blot (WB)
Application Notes
Western Blot: 1:1000
Immunogen
A synthesized peptide derived from human RSK3 (Phospho-Ser360)
Immunogen Type
Peptide
Modification
Phospho-Ser360
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis RSK3 (Phospho-Ser360) using EGF treated Jurkat whole cell lysates)

Western Blot (WB) (Western blot analysis RSK3 (Phospho-Ser360) using EGF treated Jurkat whole cell lysates)
Product Categories/Family for anti-RSK3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
84,014 Da
NCBI Official Full Name
ribosomal protein S6 kinase alpha-2 isoform b
NCBI Official Synonym Full Names
ribosomal protein S6 kinase A2
NCBI Official Symbol
RPS6KA2
NCBI Official Synonym Symbols
RSK; HU-2; RSK3; p90RSK2; p90-RSK3; pp90RSK3; MAPKAPK1C; S6K-alpha; S6K-alpha2
NCBI Protein Information
ribosomal protein S6 kinase alpha-2
UniProt Protein Name
Ribosomal protein S6 kinase alpha-2
UniProt Gene Name
RPS6KA2
UniProt Synonym Gene Names
MAPKAPK1C; RSK3; S6K-alpha-2; p90-RSK 2; p90RSK2; MAPK-activated protein kinase 1c; MAPKAP kinase 1c; MAPKAPK-1c; RSK-3
UniProt Entry Name
KS6A2_HUMAN

NCBI Description

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains two non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternative splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jan 2016]

Uniprot Description

RSK3: an AGC kinase of the RSK family. Phosphorylated and activated by Erk1 and -2 in response to many growth factors, polypeptide hormones and neurotransmitters. Several phosphorylation sites are important for its activation. Possesses two kinase domains connected by a regulator linker region. Phosphorylates a wide range of substrates including ribosomal protein S6.

Protein type: AGC group; EC 2.7.11.1; Kinase, protein; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); RSK family; RSK subfamily; Translation; Tumor suppressor

Chromosomal Location of Human Ortholog: 6q27

Cellular Component: cytoplasm; cytosol; nuclear membrane; nucleoplasm; nucleus

Molecular Function: kinase activity; protein binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity

Biological Process: negative regulation of cell cycle; negative regulation of cell proliferation; positive regulation of apoptosis

Research Articles on RSK3

Similar Products

Product Notes

The RSK3 rps6ka2 (Catalog #AAA9416620) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RSK3 (Phospho-Ser360) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RSK3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000. Researchers should empirically determine the suitability of the RSK3 rps6ka2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RSK3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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