SDS-Page
(Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human cerebella tissue, K562 cell lysates, Primary antibody:47746(RRP8 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds)
Rabbit RRP8 Polyclonal Antibody | anti-RRP8 antibody
RRP8 Antibody
IHC: 1:50-300
SDS-Page
(Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human cerebella tissue, K562 cell lysates, Primary antibody:47746(RRP8 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds)
SDS-Page
(Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human cerebella tissue, K562 cell lysates, Primary antibody:47746(RRP8 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds)
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 47746(RRP8 Antibody) at dilution 1/80.(Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 47746(RRP8 Antibody) at dilution 1/80.(Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 47746(RRP8 Antibody) at dilution 1/80.(Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 47746(RRP8 Antibody) at dilution 1/80.(Original magnification: 200))
NCBI and Uniprot Product Information
Uniprot Description
Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD+/NADP+ ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
Research Articles on RRP8
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Product Notes
The RRP8 rrp8 (Catalog #AAA9430728) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RRP8 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RRP8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-2000 IHC: 1:50-300. Researchers should empirically determine the suitability of the RRP8 rrp8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RRP8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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