Rabbit anti-Mouse RPS6KC1 Polyclonal Antibody | anti-RPS6KC1 antibody

RPS6KC1, NT (RPS6KC1, RPK118, Ribosomal protein S6 kinase delta-1, 52kD ribosomal protein S6 kinase, Ribosomal S6 kinase-like protein with two PSK domains 118kD protein, SPHK1-binding protein) (APC)

Cat. Num. AAA6343964

• Gene Names: RPS6KC1; RSKL1; RPK118; S6PKh1; humS6PKh1; S6K-delta-1
• Reactivity: Mouse
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: RPS6KC1; Polyclonal Antibody; NT (RPS6KC1; RPK118; Ribosomal protein S6 kinase delta-1; 52kD ribosomal protein S6 kinase; Ribosomal S6 kinase-like protein with two PSK domains 118kD protein; SPHK1-binding protein) (APC); SPHK1-binding protein; anti-RPS6KC1 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-RPS6KC1 antibody: Immunohistochemistry (IHC), FLISA, Western Blot (WB)
• Application Notes: IHC: 1:10-50; FLISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: RPS6KC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-47 amino acids from the N-terminal region of human RPS6KC1.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(RPS6KC1 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the RPS6KC1 antibody detected the RPS6KC1 protein (arrow).)

Immunohistochemistry (IHC)

(RPS6KC1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RPS6KC1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-RPS6KC1 antibody

RPS6KC1 may be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell.

Product Categories/Family for anti-RPS6KC1 antibody

Antibodies; Protein Kinases

References

Olsen, J.V., et al. Cell 127(3):635-648(2006). Olsen, J.V., et al. Cell 127(3):635-648(2006). Liu, L., et al. Mol. Cells 19(1):39-45(2005). Lehner, B., et al. Genomics 83(1):153-167(2004). Hayashi, S., et al. J. Biol. Chem. 277(36):33319-33324(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 19923723
• NCBI GeneID: 26750
• NCBI Accession #: NP_036556.2; NP_001129610.1
• NCBI GenBank Nucleotide #: NM_012424.4
• UniProt Accession #: Q96S38; Q8TDD3; Q9NSF4; Q9UL66; B1APS8; B3KVM4; D3DTA4
• Molecular Weight: 117,273 Da
• NCBI Official Full Name: ribosomal protein S6 kinase delta-1 isoform a
• NCBI Official Synonym Full Names: ribosomal protein S6 kinase, 52kDa, polypeptide 1
• NCBI Official Symbol: RPS6KC1
• NCBI Official Synonym Symbols: RSKL1; RPK118; S6PKh1; humS6PKh1; S6K-delta-1
• NCBI Protein Information: ribosomal protein S6 kinase delta-1; SPHK1-binding protein; 52 kDa ribosomal protein S6 kinase; ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein
• UniProt Protein Name: Ribosomal protein S6 kinase delta-1
• Protein Family: Ribosomal protein S6 kinase
• UniProt Gene Name: RPS6KC1
• UniProt Synonym Gene Names: RPK118; S6K-delta-1
• UniProt Entry Name: KS6C1_HUMAN

Uniprot Description

RSKL1: an AGC kinase of the RSKL family.

Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Protein kinase, AGC; AGC group; RSKL family

Chromosomal Location of Human Ortholog: 1q41

Cellular Component: intracellular membrane-bound organelle; membrane; early endosome; cytoplasm

Molecular Function: protein serine/threonine kinase activity; protein binding; phosphoinositide binding; ATP binding

Biological Process: signal transduction; protein amino acid phosphorylation