Rabbit anti-Human, Mouse RPS6KA5 / MSK1 Polyclonal Antibody | anti-RPS6KA5 antibody
Rabbit Polyclonal (IgG) to Human RPS6KA5 / MSK1
Immunohistochemistry (IHC)
(Anti-MSK1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Western Blot (WB)
(Western blot of extracts from COS7 cells, treated with Sorbitol 0.4 M 30', using MSK1 antibody. The lane on the right is treated with the synthesized peptide.)
NCBI and Uniprot Product Information
Uniprot Description
MSK1: an AGC kinase of the RSK family. Has two kinase domains connected by a regulatory linker region. Enzyme activity requires the presence of both kinase domains. Is phosphorylated and activated by Erk as well as p38 MAPK in response to growth factors and cellular stress.
Protein type: EC 2.7.11.1; Protein kinase, AGC; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); AGC group; RSK family; MSK subfamily
Chromosomal Location of Human Ortholog: 14q31-q32.1
Cellular Component: nucleoplasm; cytoplasm; nucleus
Molecular Function: protein serine/threonine kinase activity; protein binding; magnesium ion binding; ATP binding; protein kinase activity
Biological Process: epidermal growth factor receptor signaling pathway; axon guidance; positive regulation of histone phosphorylation; nerve growth factor receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; histone phosphorylation; stress-activated MAPK cascade; activation of CREB transcription factor; toll-like receptor 3 signaling pathway; protein amino acid phosphorylation; toll-like receptor 2 signaling pathway; activation of NF-kappaB transcription factor; toll-like receptor 10 signaling pathway; toll-like receptor 5 signaling pathway; MyD88-dependent toll-like receptor signaling pathway; regulation of transcription, DNA-dependent; negative regulation of cytokine production; toll-like receptor signaling pathway; innate immune response; positive regulation of histone acetylation; positive regulation of transcription from RNA polymerase II promoter; toll-like receptor 9 signaling pathway; inflammatory response; negative regulation of transcription, DNA-dependent; toll-like receptor 4 signaling pathway
Research Articles on RPS6KA5
Similar Products
Product Notes
The RPS6KA5 rps6ka5 (Catalog #AAA244267) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human RPS6KA5 / MSK1 reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RPS6KA5 / MSK1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA (1:1000), IHC-P (10 ug/ml), WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the RPS6KA5 rps6ka5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RPS6KA5 / MSK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.