Rabbit RPS14 Polyclonal Antibody | anti-RPS14 antibody

RPS14 Polyclonal Antibody

Cat. Num. AAA2561019

• Gene Names: RPS14; S14; EMTB
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry, ELISA
• Purity: Antigen Affinity Purification
• Synonyms: RPS14; Polyclonal Antibody; RPS14 Polyclonal Antibody; 40S ribosomal protein S14; Emetine resistance; EMTB; Ribosomal protein S14; Rps14; RS14; S14; anti-RPS14 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
• Concentration: 0.84mg/mL (varies by lot)
• Sequence Length: 151

• Applicable Applications for anti-RPS14 antibody: Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: WB: 1:1000-1:5000; IHC: 1:50-1:200; ELISA: 1:5000-1:10000
• Immunogen: Fusion protein of human RPS14
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of 231 HL60 and Jurkat cell lysates using RPS14 Polyclonal Antibody at dilution of 1:700)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using RPS14 Polyclonal Antibody at dilution of 1:50(×200))

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using RPS14 Polyclonal Antibody at dilution of 1:50(×200))

Related Product Information for anti-RPS14 antibody

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Product Categories/Family for anti-RPS14 antibody

Cancer; Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 50403752
• NCBI GeneID: 6208
• UniProt Accession #: P62263
• Molecular Weight: 16 kDa
• NCBI Official Full Name: 40S ribosomal protein S14
• NCBI Official Synonym Full Names: ribosomal protein S14
• NCBI Official Symbol: RPS14
• NCBI Official Synonym Symbols: S14; EMTB
• NCBI Protein Information: 40S ribosomal protein S14
• UniProt Protein Name: 40S ribosomal protein S14
• Protein Family: Ribosomal protein
• UniProt Gene Name: RPS14
• UniProt Entry Name: RS14_HUMAN

NCBI Description

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

RPS14: a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Protein type: RNA-binding; Ribosomal; Translation

Chromosomal Location of Human Ortholog: 5q31-q33

Cellular Component: focal adhesion; membrane; mitochondrion; cytoplasm; nucleolus; cytosol

Molecular Function: structural constituent of ribosome; RNA binding; translation regulator activity; mRNA 5'-UTR binding

Biological Process: SRP-dependent cotranslational protein targeting to membrane; viral reproduction; translation; viral infectious cycle; negative regulation of transcription from RNA polymerase II promoter; translational termination; maturation of SSU-rRNA; regulation of translation; cellular protein metabolic process; translational elongation; translational initiation; mRNA catabolic process, nonsense-mediated decay; ribosomal small subunit assembly and maintenance; erythrocyte differentiation; gene expression; viral transcription

Disease: Chromosome 5q Deletion Syndrome