Mouse anti-Human RPP21 Polyclonal Antibody | anti-RPP21 antibody

RPP21 (Ribonuclease P Protein Subunit p21, RNaseP Protein p21, Ribonuclease P/MRP 21 kDa Subunit, C6orf135, CAT60, Ribonucleoprotein V)

Cat. Num. AAA6012196

• Gene Names: RPP21; CAT60; C6orf135
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: RPP21; Polyclonal Antibody; RPP21 (Ribonuclease P Protein Subunit p21; RNaseP Protein p21; Ribonuclease P/MRP 21 kDa Subunit; C6orf135; CAT60; Ribonucleoprotein V); Anti -RPP21 (Ribonuclease P Protein Subunit p21; anti-RPP21 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human RPP21.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MAGPVKDREAFQRLNFLYQAAHCVLAQDPENQALARFYCYTERTIAKRLVLRRDPSVKRTLCRGCSSLLVPGLTCTHRQRRCRGQRWTVQTCLTCQRSQRFLNDPGHLLWGDRPEAQLGSQADSKPLQPLPNTAHSISDRLPEEKMQTQGSSNQ

• Applicable Applications for anti-RPP21 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human RPP21, aa1-154 (AAH11730.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of RPP21 expression in transfected 293T cell line by RPP21 polyclonal antibody. Lane 1: RPP21 transfected lysate (16.94kD). Lane 2: Non-transfected lysate.)

Product Categories/Family for anti-RPP21 antibody

Antibodies; Abs to Enzymes; Ribonuclease

NCBI and Uniprot Product Information

• NCBI GI #: 312283732
• NCBI GeneID: 79897
• NCBI Accession #: NP_001186050.1
• NCBI GenBank Nucleotide #: NM_001199121.1
• UniProt Accession #: Q9H633; Q5JPL9; Q5JPM1; Q5STF8; Q5STF9; Q5STG2; Q5SU41; Q5SU42; Q86Y49; A2AAZ8; B0S834; B0S835
• Molecular Weight: 17,570 Da
• NCBI Official Full Name: ribonuclease P protein subunit p21 isoform 3
• NCBI Official Synonym Full Names: ribonuclease P/MRP 21kDa subunit
• NCBI Official Symbol: RPP21
• NCBI Official Synonym Symbols: CAT60; C6orf135
• NCBI Protein Information: ribonuclease P protein subunit p21; RNaseP protein p21; ribonucleoprotein V
• UniProt Protein Name: Ribonuclease P protein subunit p21
• Protein Family: Ribonuclease P protein
• UniProt Gene Name: RPP21
• UniProt Synonym Gene Names: C6orf135; CAT60; RNaseP protein p21
• UniProt Entry Name: RPP21_HUMAN

NCBI Description

RPP21 is a protein subunit of nuclear ribonuclease P, which processes the 5-prime leader sequence of precursor tRNAs (Jarrous et al., 2001 [PubMed 11497433]).[supplied by OMIM, Jan 2009]

Uniprot Description

RPP21: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 4 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleolus; EC 3.1.26.5; Ribonuclease

Chromosomal Location of Human Ortholog: 6p22.1

Cellular Component: nucleolus

Molecular Function: metal ion binding; ribonuclease P activity

Biological Process: response to drug; tRNA processing