Rabbit RNF31/HOIP Polyclonal Antibody | anti-RNF31 antibody

Anti-RNF31/HOIP Antibody

Cat. Num. AAA1752511

• Gene Names: RNF31; HOIP; Paul; ZIBRA
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, ELISA
• Purity: Immunogen Affinity Purified
• Synonyms: RNF31/HOIP; Polyclonal Antibody; Anti-RNF31/HOIP Antibody; E3 ubiquitin-protein ligase RNF31; ring finger protein 31; HOIL-1-interacting protein; HOIP; RING finger protein 31; RING-type E3 ubiquitin transferase RNF31; Zinc in-between-RING-finger ubiquitin-associated domain protein; RNF31; ZIBRA; anti-RNF31 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: No cross reactivity with other proteins.
• Purity/Purification: Immunogen Affinity Purified
• Form/Format: Lyophilized
• Sequence Length: 1072

• Applicable Applications for anti-RNF31 antibody: Western Blot (WB), Direct ELISA (EIA)
• Application Notes: WB: 0.1-0.5ug/ml; Direct ELISA: 0.1-0.5ug/ml
• Immunogen: E Coli-derived human RNF31/HOIP recombinant protein (Position: R970-K1072).
• Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Relevant Detection Systems: Relevant Detection Systems
• Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500mug/ml.
• Relevant Detection Systems: Relevant Detection Systems
• Relevant Detection Systems: We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (MBS176460) for Western blot.
• Preparation and Storage: At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Related Product Information for anti-RNF31 antibody

Description: Rabbit IgG polyclonal antibody for RNF31/HOIP detection. Tested with WB, Direct ELISA in Human; Mouse; Rat.

Background: RING finger protein 31 is a protein that in humans is encoded by the RNF31 gene. It is mapped to 14q12. The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. The encoded protein is the E3 ubiquitin-protein ligase component of the linear ubiquitin chain assembly complex. Two transcript variants encoding different isoforms have been found for this gene. 

References

1. Ikeda, F., Deribe, Y. L., Skanland, S. S., Stieglitz, B., Grabbe, C., Franz-Wachtel, M., van Wijk, S. J. L., Goswami, P., Nagy, V., Terzic, J., Tokunaga, F., Androulidaki, A., Nakagawa, T., Pasparakis, M., Iwai, K., Sundberg, J. P., Schaefer, L., Rittinger, K., Macek, B., Dikic, I. SHARPIN forms a linear ubiquitin ligase complex regulating NF-kappa-B activity and apoptosis.Nature 471: 637-641, 2011.  2. Thompson, H. G. R., Harris, J. W., Lin, L., Brody, J. P. Identification of the protein Zibra, its genomic organization, regulation, and expression in breast cancer cells. Exp. Cell Res. 295: 448-459, 2004.

NCBI and Uniprot Product Information

• NCBI GI #: 109150431
• NCBI GeneID: 55072
• NCBI Accession #: NP_060469
• NCBI GenBank Nucleotide #: NP_060469.4
• UniProt Accession #: Q96EP0
• NCBI Official Full Name: E3 ubiquitin-protein ligase RNF31 isoform 1
• NCBI Official Synonym Full Names: ring finger protein 31
• NCBI Official Symbol: RNF31
• NCBI Official Synonym Symbols: HOIP; Paul; ZIBRA
• NCBI Protein Information: E3 ubiquitin-protein ligase RNF31
• UniProt Protein Name: E3 ubiquitin-protein ligase RNF31
• Protein Family: E3 ubiquitin-protein ligase
• UniProt Gene Name: RNF31
• UniProt Synonym Gene Names: ZIBRA; HOIP
• UniProt Entry Name: RNF31_HUMAN

NCBI Description

The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. The encoded protein is the E3 ubiquitin-protein ligase component of the linear ubiquitin chain assembly complex. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]