Western Blot (WB)
((0.3ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat RNASEN/Drosha Polyclonal Antibody | anti-RNASEN antibody
Goat anti-RNASEN/Drosha Antibody
Western Blot: Approx 150-160kDa band observed in Human Liver lysates (calculated MW of 151kDa according to NP_081075.2). Recommended concentration: 0.3-1ug/ml.
Western Blot (WB)
((0.3ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((0.3ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
Uniprot Description
DROSHA: a nuclear type-III RNase that, along with the DGCR8, executes the initial step of microRNA (miRNA) processing in the nucleus. Cleaves the local hairpin structures embedded in long primary microRNA transcripts (pri-miRNAs) into pre-miRNAs. Involved in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Interacts with Sp1. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleolus; Ribonuclease; RNA-binding; RNA processing; EC 3.1.26.3
Cellular Component: nucleus
Molecular Function: double-stranded RNA binding; endonuclease activity; endoribonuclease activity; hydrolase activity; lipopolysaccharide binding; metal ion binding; nuclease activity; protein binding; protein homodimerization activity; ribonuclease III activity; RNA binding
Biological Process: defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; pre-microRNA processing; primary microRNA processing; regulation of gene expression; ribosome biogenesis and assembly; RNA interference, production of siRNA; RNA processing; rRNA catabolic process
Research Articles on RNASEN
Similar Products
Product Notes
The RNASEN drosha (Catalog #AAA421018) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-RNASEN/Drosha Antibody reacts with Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's RNASEN/Drosha can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Approx 150-160kDa band observed in Human Liver lysates (calculated MW of 151kDa according to NP_081075.2). Recommended concentration: 0.3-1ug/ml. Researchers should empirically determine the suitability of the RNASEN drosha for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: KQTDKQKLAQ RE. It is sometimes possible for the material contained within the vial of "RNASEN/Drosha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
