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Western Blot (WB) (Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: 293T cell lysate, Primary antibody: 824185(USP6NL Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes)

Rabbit anti-Human RN-tre Polyclonal Antibody | anti-RN-tre antibody

RN-tre Rabbit pAb

Gene Names
USP6NL; RNTRE; TRE2NL; USP6NL-IT1
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
RN-tre; Polyclonal Antibody; RN-tre Rabbit pAb; RNTRE; TRE2NL; USP6NL-IT1; anti-RN-tre antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity purified
Form/Format
-20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-RN-tre antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:500-1:2000
Immunogen
Fusion protein of human USP6NL
Conjugation
Unconjugated
Molecular Function
Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR.
Modification
Unmodified
Cell Position
Cytoplasmic vesicle, Golgi apparatus
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: 293T cell lysate, Primary antibody: 824185(USP6NL Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes)

Western Blot (WB) (Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: 293T cell lysate, Primary antibody: 824185(USP6NL Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 824185(USP6NL Antibody) at dilution 1/30. (Original magnification: ×200))

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 824185(USP6NL Antibody) at dilution 1/30. (Original magnification: ×200))
Product Categories/Family for anti-RN-tre antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
95,997 Da
NCBI Official Full Name
Homo sapiens USP6 N-terminal like, mRNA
NCBI Official Synonym Full Names
USP6 N-terminal like
NCBI Official Symbol
USP6NL
NCBI Official Synonym Symbols
RNTRE; TRE2NL; USP6NL-IT1
NCBI Protein Information
USP6 N-terminal-like protein
UniProt Protein Name
USP6 N-terminal-like protein
UniProt Gene Name
USP6NL
UniProt Synonym Gene Names
KIAA0019; RN-tre
UniProt Entry Name
US6NL_HUMAN

Uniprot Description

USP6NL: a widely-expressed GTPase activating protein (GAP) for RAB5A. Involved in endosomal trafficking, and localizes to the centrosome. In complex with Eps8 inhibits internalization of EGFR.

Protein type: GAPs, Rab; GAPs; Ubiquitin-specific protease

Chromosomal Location of Human Ortholog: 10p13

Cellular Component: Golgi apparatus; cytoplasmic membrane-bound vesicle; plasma membrane; cytoplasmic vesicle

Molecular Function: Rab GTPase binding

Biological Process: plasma membrane to endosome transport; virus assembly; Golgi organization and biogenesis

Research Articles on RN-tre

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Product Notes

The RN-tre usp6nl (Catalog #AAA4758144) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RN-tre Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RN-tre can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the RN-tre usp6nl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RN-tre, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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