Immunohistochemistry (IHC)
(Fig: 1 Immunohistochemical analysis of RIP in formalin-fixed, paraffin-embedded tonsil using at 1: 2000. A, low magnification overview of a secondary follicle. A1 and A2, sucessively higher magnifications of the germinal center from A. Hematoxylin-eosin counterstain.)
Rabbit anti-Human RIP Polyclonal Antibody | anti-RIP antibody
Polyclonal Antibody to RIP
IHC (paraffin): 1: 1000-1: 5000
IP: 1: 50-1: 200
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
Immunohistochemistry (IHC)
(Fig: 1 Immunohistochemical analysis of RIP in formalin-fixed, paraffin-embedded tonsil using at 1: 2000. A, low magnification overview of a secondary follicle. A1 and A2, sucessively higher magnifications of the germinal center from A. Hematoxylin-eosin counterstain.)
Immunohistochemistry (IHC)
(Fig: 1 Immunohistochemical analysis of RIP in formalin-fixed, paraffin-embedded tonsil using at 1: 2000. A, low magnification overview of a secondary follicle. A1 and A2, sucessively higher magnifications of the germinal center from A. Hematoxylin-eosin counterstain.)
Immunohistochemistry (IHC)
(Fig: 2 Immunohistochemical analysis of RIP in formalin-fixed, paraffin-embedded tissue sections using at 1: 2000. A, normal human breast. B, normal human colon. Plasma cells in the lamina propia of the colon are stained. Hematoxylin-eosin counterstain.)
Immunohistochemistry (IHC)
(Fig: 2 Immunohistochemical analysis of RIP in formalin-fixed, paraffin-embedded tissue sections using at 1: 2000. A, normal human breast. B, normal human colon. Plasma cells in the lamina propia of the colon are stained. Hematoxylin-eosin counterstain.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Uniprot Description
RIP: Required for vesicle docking or fusion during acrosome biogenesis. May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element- containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication. Interacts with EPS15R and EPS15. Interacts with FCHO1. Ubiquitously expressed. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear export; RNA-binding
Chromosomal Location of Human Ortholog: 2q36.3
Cellular Component: intracellular membrane-bound organelle; nuclear pore
Molecular Function: protein binding; RNA binding
Biological Process: mRNA export from nucleus
Research Articles on RIP
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Product Notes
The RIP agfg1 (Catalog #AAA668767) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to RIP reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RIP can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB). WB: 1: 1000-1: 2000 IHC (paraffin): 1: 1000-1: 5000 IP: 1: 50-1: 200. Researchers should empirically determine the suitability of the RIP agfg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RIP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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