Western Blot (WB)
(RIC8A Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the RIC8A antibody detected the RIC8A protein (arrow).)
Rabbit anti-Human RIC8A Polyclonal Antibody | anti-RIC8A antibody
RIC8A, ID (RIC8A, Synembryn-A, Protein Ric-8A) (FITC)
Gene Names
RIC8A; RIC8
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
RIC8A; Polyclonal Antibody; ID (RIC8A; Synembryn-A; Protein Ric-8A) (FITC); Protein Ric-8A; anti-RIC8A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Applicable Applications for anti-RIC8A antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
RIC8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-271 amino acids from the Central region of human RIC8A.
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(RIC8A Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the RIC8A antibody detected the RIC8A protein (arrow).)
Western Blot (WB)
(RIC8A Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the RIC8A antibody detected the RIC8A protein (arrow).)
Related Product Information for anti-RIC8A antibody
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
Product Categories/Family for anti-RIC8A antibody
References
Woodard, G.E., et al. Mol. Cell. Biol. 30(14):3519-3530(2010). Matsuoka, S., et al. Science 316(5828):1160-1166(2007). Lim, J., et al. Cell 125(4):801-814(2006). Nishimura, A., et al. Genes Cells 11(5):487-498(2006). Tall, G.G., et al. J. Biol. Chem. 278(10):8356-8362(2003).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
531
NCBI Official Full Name
synembryn-A
NCBI Official Synonym Full Names
RIC8 guanine nucleotide exchange factor A
NCBI Official Symbol
RIC8A
NCBI Official Synonym Symbols
RIC8
NCBI Protein Information
synembryn-A; resistance to inhibitors of cholinesterase 8 homolog A
UniProt Protein Name
Synembryn-A
Protein Family
UniProt Gene Name
RIC8A
UniProt Entry Name
RIC8A_HUMAN
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Product Notes
The RIC8A ric8a (Catalog #AAA6342096) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RIC8A, ID (RIC8A, Synembryn-A, Protein Ric-8A) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RIC8A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the RIC8A ric8a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RIC8A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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