Rabbit RHEB Polyclonal Antibody | anti-RHEB antibody
RHEB
Gene Names
RHEB; RHEB2
Reactivity
HumanPredicted: Rat, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Purified By Antigen Affinity Column
Synonyms
RHEB; Polyclonal Antibody; RHEB2; anti-RHEB antibody
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
1396
Applicable Applications for anti-RHEB antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-80,000
WB: 1:200-1,000
IHC: 1:100-500
WB: 1:200-1,000
IHC: 1:100-500
Immunogen
Recombinant fragment corresponding to 18-180aa of human RHEB.
Cellular Localization
Cytoplasm, Endoplasmic Reticulum, Golgi Apparatus, Membrane
Related Product Information for anti-RHEB antibody
Homo sapiens Ras homolog enriched in brain, mRNA
References
Sato T, Akasu H, Shimono W, et al. Rheb protein binds CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamoylase, and dihydroorotase) protein in a GTP-and effector domain-dependent manner and influences its cellular localization and carbamoyl-phosphate synthetase (CPSase) activity. J Biol Chem. 290(2):1096-105 (2015)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
17KD
NCBI Official Full Name
Homo sapiens Ras homolog enriched in brain, mRNA
NCBI Official Synonym Full Names
Ras homolog, mTORC1 binding
NCBI Official Symbol
RHEB
NCBI Official Synonym Symbols
RHEB2
NCBI Protein Information
GTP-binding protein Rheb
Protein Family
NCBI Description
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008]
Research Articles on RHEB
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Product Notes
The RHEB (Catalog #AAA8561124) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RHEB reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RHEB can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-80,000 WB: 1:200-1,000 IHC: 1:100-500. Researchers should empirically determine the suitability of the RHEB for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RHEB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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