Western Blot (WB)
(RHD Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RHD antibody detected the RHD protein (arrow).)
Rabbit anti-Human RHD Polyclonal Antibody | anti-RHD antibody
RHD Antibody (Center)
Western Blot (WB)
(RHD Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RHD antibody detected the RHD protein (arrow).)
Western Blot (WB)
(RHD Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RHD antibody detected the RHD protein (arrow).)
significant of the blood groups, second only to ABO. It is also the
most polymorphic of the blood groups, with variations due to
deletions, gene conversions, and missense mutations. The Rh blood
group includes this gene, which encodes the RhD protein, and a
second gene that encodes both the RhC and RhE antigens on a single
polypeptide. The two genes, and a third unrelated gene, are found
in a cluster on chromosome 1. The classification of Rh-positive and
Rh-negative individuals is determined by the presence or absence of
the highly immunogenic RhD protein on the surface of erythrocytes.
Multiple transcript variants encoding different isoforms have been
found for this gene.
Liu, H.C., et al. Biochim. Biophys. Acta 1800(6):565-573(2010)
Schmid, P., et al. Transfusion 50(1):267-269(2010)
Wang, X.D., et al. Eur. J. Clin. Invest. 39(7):607-617(2009)
Wagner, F.F., et al. Blood 99(6):2272-2273(2002)
NCBI and Uniprot Product Information
NCBI Description
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
RHD: May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1p36.11
Cellular Component: integral to plasma membrane
Molecular Function: ammonium transmembrane transporter activity
Research Articles on RHD
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Product Notes
The RHD rhd (Catalog #AAA9202028) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 173-201. The RHD Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RHD can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the RHD rhd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RHD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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