Western Blot (WB)
(Western Blot analysis of JAZF1 expression in transfected 293T cell line by JAZF1 polyclonal antibody. Lane 1: JAZF1 transfected lysate (26.73kD). Lane 2: Non-transfected lysate.)
Mouse anti-Human JAZF1 Polyclonal Antibody | anti-JAZF1 antibody
JAZF1 (TIP27, ZNF802, Juxtaposed with Another Zinc Finger Protein 1, TAK1-interacting Protein 27, Zinc Finger Protein 802, DKFZp761K2222)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of JAZF1 expression in transfected 293T cell line by JAZF1 polyclonal antibody. Lane 1: JAZF1 transfected lysate (26.73kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of JAZF1 expression in transfected 293T cell line by JAZF1 polyclonal antibody. Lane 1: JAZF1 transfected lysate (26.73kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized [provided by RefSeq, Jul 2008]
Uniprot Description
JAZF1: Potential transcription factor. A chromosomal aberration involving JAZF1 may be a cause of endometrial stromal tumors. Translocation t(7;17)(p15;q21) with SUZ12. The translocation generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor co-regulator; C2H2-type zinc finger protein; Transcription, coactivator/corepressor; Oncoprotein
Chromosomal Location of Human Ortholog: 7p15.2-p15.1
Cellular Component: transcriptional repressor complex; nucleus
Molecular Function: nucleic acid binding; metal ion binding; transcription corepressor activity
Biological Process: transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter
Research Articles on JAZF1
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Product Notes
The JAZF1 jazf1 (Catalog #AAA643832) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The JAZF1 (TIP27, ZNF802, Juxtaposed with Another Zinc Finger Protein 1, TAK1-interacting Protein 27, Zinc Finger Protein 802, DKFZp761K2222) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's JAZF1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the JAZF1 jazf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MTGIAAASFF SNTCRFGGCG LHFPTLADLI EHIEDNHIDT DPRVLEKQEL QQPTYVALSY INRFMTDAAR REQESLKKKI QPKLSLTLSS SVSRGNVSTP PRHSSGSLTP PVTPPITPSS SFRSSTPTGS EYGEEEVDYE ESDSDESWTT ESAISSEAIL SSMCMNGGEE KPFACPVPGC KKRYKNVNGI KYHAKNGHRT QIRVRKPFKC RCGKSYKTAQ GLRHHTINFH PPVSAEIIRK MQQ. It is sometimes possible for the material contained within the vial of "JAZF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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