Rabbit RGS6 Polyclonal Antibody | anti-RGS6 antibody
RGS6 Antibody
Gene Names
RGS6; GAP
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
RGS6; Polyclonal Antibody; RGS6 Antibody; FLJ43552; G protein signaling 6 regulator; GAP; GTPase activating protein; MGC142132; Regulator of G protein signaling 6; Regulator of G protein signalling 6; Regulator of G-protein signaling 6; RGS 6; RGS6_HUMAN; S914; anti-RGS6 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
RGS6 Antibody detects endogenous levels of RGS6.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-RGS6 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human RGS6.
Conjugation
Unconjugated
Similarity
The RGS domain interacts avidly with Galpha and mediates the acceleration of Galpha-mediated GTP hydrolysis.
Subunit Structure
Interacts with GNB5. Interacts with RGS7BP, leading to regulate the subcellular location of the heterodimer formed with GNB5 (By similarity). Interacts with GNAI1.
Function
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity.
Note
Interaction with GNB5 mediates translocation to the nucleus.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-RGS6 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,319 Da
NCBI Official Full Name
regulator of G-protein signaling 6 isoform 1
NCBI Official Synonym Full Names
regulator of G-protein signaling 6
NCBI Official Symbol
RGS6
NCBI Official Synonym Symbols
GAP
NCBI Protein Information
regulator of G-protein signaling 6; GTPase activating protein; H_DJ1108A12.1; S914; WUGSC:H_DJ0283M22.1; WUGSC:H_DJ1108A12.1; regulator of G-protein signalling 6
UniProt Protein Name
Regulator of G-protein signaling 6
Protein Family
UniProt Gene Name
RGS6
UniProt Synonym Gene Names
RGS6
UniProt Entry Name
RGS6_HUMAN
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Product Notes
The RGS6 rgs6 (Catalog #AAA9630654) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RGS6 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RGS6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the RGS6 rgs6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RGS6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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