Western Blot (WB)
(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Hela cells, hepg2 cells, Primary antibody: 823017(RGS22 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)
Rabbit anti-Human RGS22 Polyclonal Antibody | anti-RGS22 antibody
RGS22 Rabbit pAb
Gene Names
RGS22; CT145; PRTD-NY2
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
RGS22; Polyclonal Antibody; RGS22 Rabbit pAb; CT145; PRTD-NY2; anti-RGS22 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity purified
Form/Format
-20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-RGS22 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:500-1:2000
Immunogen
Fusion protein of human RGS22
Conjugation
Unconjugated
Molecular Function
RGS22 (regulator of G-protein signaling 22), also known as FLJ75004, PRTD-NY2, FLJ40080, MGC102908 or DKFZp434I092, is a novel 1264 amino acid regulator of G-protein signaling specific to to testis. RGS22 inhibits signal transduction and contains two isoforms as a result of alternative splicing. RGS22 is found in spermatogenic cells and Leydig cells, and may be involved in the translocation of GNA13 from the cytoplasm to the nucleus during spermiogenesis. RGS22 contains two RGS domains: RGS1 and RGS2, and the gene encoding RGS22 maps to human chromosome 8q22.2.
Modification
Unmodified
Cell Position
Cytoplasm, Nucleus
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.
Western Blot (WB)
(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Hela cells, hepg2 cells, Primary antibody: 823017(RGS22 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)
Western Blot (WB)
(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Hela cells, hepg2 cells, Primary antibody: 823017(RGS22 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 823017(RGS22 Antibody) at dilution 1/40. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 823017(RGS22 Antibody) at dilution 1/40. (Original magnification: ×200))
Product Categories/Family for anti-RGS22 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
145,768 Da
NCBI Official Full Name
Homo sapiens regulator of G-protein signaling 22, mRNA
NCBI Official Synonym Full Names
regulator of G-protein signaling 22
NCBI Official Symbol
RGS22
NCBI Official Synonym Symbols
CT145; PRTD-NY2
NCBI Protein Information
regulator of G-protein signaling 22
UniProt Protein Name
Regulator of G-protein signaling 22
Protein Family
UniProt Gene Name
RGS22
UniProt Synonym Gene Names
RGS22
UniProt Entry Name
RGS22_HUMAN
Uniprot Description
RGS22: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs, RGS; GAPs; Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: 8q22.2
Cellular Component: cytoplasm; plasma membrane; nucleus
Molecular Function: GTPase activator activity
Biological Process: positive regulation of GTPase activity
Research Articles on RGS22
Similar Products
Product Notes
The RGS22 rgs22 (Catalog #AAA4758045) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RGS22 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RGS22 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the RGS22 rgs22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RGS22, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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