Western Blot (WB)
(Western Blot analysis of RGN in Human fetal liver tissue lysate using RGN Rabbit pAb at dilution 1/450)
Rabbit RGN Polyclonal Antibody | anti-RGN antibody
RGN Rabbit pAb
IHC-P: 1:25-1:100
Western Blot (WB)
(Western Blot analysis of RGN in Human fetal liver tissue lysate using RGN Rabbit pAb at dilution 1/450)
Western Blot (WB)
(Western Blot analysis of RGN in Human fetal liver tissue lysate using RGN Rabbit pAb at dilution 1/450)
Immunohistochemistry (IHC)
(Immunohistochemistry of RGN in paraffin-embedded Human liver cancer tissue using RGN Rabbit pAb at dilution 1/25. Predicted cell location: Cytoplasm or Nucleus)
Immunohistochemistry (IHC)
(Immunohistochemistry of RGN in paraffin-embedded Human liver cancer tissue using RGN Rabbit pAb at dilution 1/25. Predicted cell location: Cytoplasm or Nucleus)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Uniprot Description
RGN: Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities. Belongs to the SMP-30/CGR1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.1.17
Chromosomal Location of Human Ortholog: Xp11.3
Cellular Component: nucleoplasm; cytoplasm; nucleus
Molecular Function: zinc ion binding; gluconolactonase activity; calcium ion binding; enzyme regulator activity
Biological Process: cellular calcium ion homeostasis; L-ascorbic acid biosynthetic process; positive regulation of ATPase activity; regulation of calcium-mediated signaling
Research Articles on RGN
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Product Notes
The RGN rgn (Catalog #AAA4759749) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RGN Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RGN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000 IHC-P: 1:25-1:100. Researchers should empirically determine the suitability of the RGN rgn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RGN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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