Rabbit anti-Human REV3L Polyclonal Antibody | anti-REV3L antibody
REV3L Polyclonal Antibody
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene represents the catalytic subunit of DNA polymerase zeta, which functions in translesion DNA synthesis. The encoded protein can be found in mitochondria, where it protects DNA from damage. Defects in this gene are a cause of Mobius syndrome. [provided by RefSeq, Jan 2017]
Uniprot Description
REV3: the DNA polymerase zeta catalytic subunit. Catalyzes the production of N diphosphate + {DNA}N from N deoxynucleoside triphosphate. Involved in translesion synthesis and required for the production of UV- and other DNA fork-blocking-induced mutations, as well as the majority of spontaneous mutations.
Protein type: Transferase; EC 2.7.7.7; DNA replication
Chromosomal Location of Human Ortholog: 6q21
Cellular Component: nucleoplasm; zeta DNA polymerase complex; nucleolus; nucleus
Molecular Function: protein binding; DNA binding; metal ion binding; 4 iron, 4 sulfur cluster binding; DNA-directed DNA polymerase activity; nucleotide binding
Biological Process: error-prone postreplication DNA repair; DNA-dependent DNA replication; DNA repair
Research Articles on REV3L
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Product Notes
The REV3L rev3l (Catalog #AAA8566682) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The REV3L Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's REV3L can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the REV3L rev3l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "REV3L, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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