Rabbit anti-Human RERG Polyclonal Antibody | anti-RERG antibody
RERG Antibody, HRP conjugated
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
NCBI and Uniprot Product Information
NCBI Description
RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]).[supplied by OMIM, Mar 2009]
Uniprot Description
RERG: Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential. Belongs to the small GTPase superfamily. Ras family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: G protein, monomeric, Ras; G protein, monomeric; G protein
Chromosomal Location of Human Ortholog: 12p12.3
Cellular Component: cytosol; membrane; nucleus
Molecular Function: estrogen receptor binding; GDP binding; GTP binding; GTPase activity
Biological Process: negative regulation of cell growth; negative regulation of cell proliferation; response to hormone stimulus; small GTPase mediated signal transduction