Rabbit anti-Human, Mouse Reptin Polyclonal Antibody | anti-RUVBL2 antibody

Reptin, CT (RuvB-like 2, 48kD TATA Box-binding Protein-interacting Protein, 48kD TBP-Interacting Protein, TIP49b, Repressing Pontin 52, Reptin 52, 51kD Erythrocyte Cytosolic Protein, ECP-51, TIP60-associated Protein 54-beta, TAP54-beta, TIP48, TIP49B, RUV

Cat. Num. AAA6498357

• Gene Names: RUVBL2; RVB2; TIH2; ECP51; TIP48; CGI-46; INO80J; REPTIN; TIP49B
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A/G Affinity Chromatography.
• Synonyms: Reptin; Polyclonal Antibody; CT (RuvB-like 2; 48kD TATA Box-binding Protein-interacting Protein; 48kD TBP-Interacting Protein; TIP49b; Repressing Pontin 52; Reptin 52; 51kD Erythrocyte Cytosolic Protein; ECP-51; TIP60-associated Protein 54-beta; TAP54-beta; TIP48; TIP49B; RUV; anti-RUVBL2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human Reptin. Species Crossreactivity: mouse.
• Purity/Purification: Purified by Protein A/G Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-RUVBL2 antibody: FLISA, Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 400-430 in the C-terminal region of human Reptin. Species Crossreactivity: bovine and xenopus.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis detects RUVBL2 in mouse kidney (left) and SK-Br-3 (right) tissue/cell linel ysates using MBS628914.)

Western Blot (WB)

(Western Blot analysis of RUVBL2 (arrow) of 293 cell lysates (2ug/lane) using MBS628914. Lane 1: Nontransfected with the RUVBL2 gene. Lane 2: Transfected with the RUVBL2 gene)

Related Product Information for anti-RUVBL2 antibody

This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.

Product Categories/Family for anti-RUVBL2 antibody

Antibodies; Enzymes

References

1. Bauer, A., et al., EMBO J. 19(22):6121-6130 (2000). 2. Parfait, B., et al., Ann. Genet. 43(2):69-74 (2000). 3. Wood, M.A., et al., Mol. Cell 5(2):321-330 (2000). 4. Salzer, U., et al., Biochim. Biophys. Acta 1446(3):365-370 (1999). 5. Kanemaki, M., et al., J. Biol. Chem. 274(32):22437-22444 (1999).

NCBI and Uniprot Product Information

• NCBI GI #: 5730023
• NCBI GeneID: 10856
• NCBI Accession #: NP_006657
• NCBI GenBank Nucleotide #: NM_006666
• UniProt Accession #: Q6FIB9; Q6PK27; Q9Y361; B3KQ59; E7ETE5; Q9Y230
• Molecular Weight: 46,306 Da
• NCBI Official Full Name: ruvB-like 2
• NCBI Official Synonym Full Names: RuvB-like AAA ATPase 2
• NCBI Official Symbol: RUVBL2
• NCBI Official Synonym Symbols: RVB2; TIH2; ECP51; TIP48; CGI-46; INO80J; REPTIN; TIP49B
• NCBI Protein Information: ruvB-like 2; 48 kDa TATA box-binding protein-interacting protein; 48 kDa TBP-interacting protein; 51 kDa erythrocyte cytosolic protein; ECP-51; INO80 complex subunit J; RuvB (E coli homolog)-like 2; TAP54-beta; TIP60-associated protein 54-beta; erythrocyt
• Protein Family: RuvB