Knockout Validation
(Knockout Validation: Lane 1: Wild-type WERI-RB-1 cell lysate; Lane 2: RCVRN knockout WERI-RB-1 cell lysate; Predicted MW: 23kd Observed MW: 22kd Primary Ab: 2ug/ml Rabbit Anti-Human RCVRN Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))
Rabbit anti-Human Recoverin (RCVRN) Polyclonal Antibody | anti-RCVRN antibody
Cy3-Linked Polyclonal Antibody to Recoverin (RCVRN)
Knockout Validation
(Knockout Validation: Lane 1: Wild-type WERI-RB-1 cell lysate; Lane 2: RCVRN knockout WERI-RB-1 cell lysate; Predicted MW: 23kd Observed MW: 22kd Primary Ab: 2ug/ml Rabbit Anti-Human RCVRN Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))
Knockout Validation
(Knockout Validation: Lane 1: Wild-type WERI-RB-1 cell lysate; Lane 2: RCVRN knockout WERI-RB-1 cell lysate; Predicted MW: 23kd Observed MW: 22kd Primary Ab: 2ug/ml Rabbit Anti-Human RCVRN Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy. [provided by RefSeq, Jul 2008]
Uniprot Description
RCV1: Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse. Belongs to the recoverin family.
Protein type: Calcium-binding
Chromosomal Location of Human Ortholog: 17p13.1
Molecular Function: calcium sensitive guanylate cyclase activator activity
Biological Process: signal transduction
Research Articles on RCVRN
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Product Notes
The RCVRN rcvrn (Catalog #AAA2076661) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cy3-Linked Polyclonal Antibody to Recoverin (RCVRN) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Recoverin (RCVRN) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA). Researchers should empirically determine the suitability of the RCVRN rcvrn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Recoverin (RCVRN), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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