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Rabbit anti-Human RCAN3 Polyclonal Antibody | anti-RCAN3 antibody

RCAN3 Antibody

Gene Names
RCAN3; RCN3; MCIP3; hRCN3; DSCR1L2
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
RCAN3; Polyclonal Antibody; RCAN3 Antibody; Calcipressin-3; Down syndrome candidate region 1 like 2; regulator of calcineurin 3; Down syndrome candidate region 1 like protein 2; Down syndrome candidate region 1-like protein 2; Down syndrome critical region gene 1 like 2; DSCR1L2; hRCN3; MCIP3; Myocyte enriched calcineurin interacting protein 3; Myocyte-enriched calcineurin-interacting protein 3; RCAN family member 3; RCAN3_HUMAN; RCN3; Regulator of calcineurin 3; Regulator of calcineurin 3 isoform 1b; 2; anti-RCAN3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
RCAN3 Antibody detects endogenous levels of RCAN3.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-RCAN3 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human RCAN3.
Conjugation
Unconjugated
Similarity
Belongs to the RCAN family.
Subunit Structure
Interacts with protein phosphatase PPP3CA/calcineurin A.
Tissue Specificity
Highest expression in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Lower expression in all other tissues.
Function
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-RCAN3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
12,745 Da
NCBI Official Full Name
calcipressin-3 isoform 1
NCBI Official Synonym Full Names
RCAN family member 3
NCBI Official Symbol
RCAN3
NCBI Official Synonym Symbols
RCN3; MCIP3; hRCN3; DSCR1L2
NCBI Protein Information
calcipressin-3; Down syndrome candidate region 1-like 2; Down syndrome critical region gene 1-like 2; down syndrome candidate region 1-like protein 2; myocyte-enriched calcineurin-interacting protein 3; regulator of calcineurin 3 isoform 1b,2
UniProt Protein Name
Calcipressin-3
Protein Family
UniProt Gene Name
RCAN3
UniProt Synonym Gene Names
DSCR1L2; MCIP3
UniProt Entry Name
RCAN3_HUMAN

Uniprot Description

RCAN3: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. Belongs to the RCAN family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 1p36.11

Molecular Function: RNA binding; troponin I binding

Biological Process: anatomical structure morphogenesis; calcium-mediated signaling

Research Articles on RCAN3

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Product Notes

The RCAN3 rcan3 (Catalog #AAA9630887) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RCAN3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RCAN3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the RCAN3 rcan3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RCAN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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