Rabbit anti-Human RBMY1A1 Polyclonal Antibody | anti-RBMY1A1 antibody

RBMY1A1 Antibody

Cat. Num. AAA7123074

• Gene Names: RBMY1A1; RBM; RBM1; RBM2; RBMY; YRRM1; YRRM2; RBMY1C; MGC181956
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Antigen Affinity Purification
• Synonyms: RBMY1A1; Polyclonal Antibody; RBMY1A1 Antibody; RNA binding motif protein; Y-linked; family 1; member A1; anti-RBMY1A1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol

• Applicable Applications for anti-RBMY1A1 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: ELISA: 1:2000-1:5000; WB: 1:500-1:2000
• Immunogen: Fusion protein of human RBMY1A1
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

SDS-PAGE

(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-4: A549 cells, Hela cells, PC3 cells, HepG2 cells, Primary antibody: MBS7123074(RBMY1A1 Antibody) at dilution 1/360, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds)

Product Categories/Family for anti-RBMY1A1 antibody

Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 4826974
• NCBI GeneID: 5940
• NCBI Accession #: NP_005049.1
• NCBI GenBank Nucleotide #: NM_005058.2
• UniProt Accession #: P0DJD3; Q15376; Q15377; Q6NSB5; Q86VU6; Q8NHR0; Q13369; Q15414
• Molecular Weight: 55,784 Da
• NCBI Official Full Name: RNA-binding motif protein, Y chromosome, family 1 member A1/C
• NCBI Official Synonym Full Names: RNA binding motif protein, Y-linked, family 1, member A1
• NCBI Official Symbol: RBMY1A1
• NCBI Official Synonym Symbols: RBM; RBM1; RBM2; RBMY; YRRM1; YRRM2; RBMY1C; MGC181956
• NCBI Protein Information: RNA-binding motif protein, Y chromosome, family 1 member A1/C; hRBMY; OTTHUMP00000040529; RNA binding protein; RNA binding motif protein 2; RNA-binding motif protein 1; RNA-binding motif protein 2; y chromosome RNA recognition motif 1; RNA binding motif p
• UniProt Protein Name: RNA-binding motif protein, Y chromosome, family 1 member A1
• Protein Family: RNA-binding motif protein
• UniProt Gene Name: RBMY1A1
• UniProt Synonym Gene Names: RBM1; RBM2; YRRM1; YRRM2; hRBMY
• UniProt Entry Name: RBY1A_HUMAN

NCBI Description

This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. [provided by RefSeq]

Uniprot Description

RBMY1A1: RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN. Binds non-specifically to mRNAs. Interacts with splicing factor proteins SFRS3/SRP20, TRA2B/SFRS10, KHDRBS1/SAM68 and KHDRBS3.

Protein type: RNA splicing

Chromosomal Location of Human Ortholog: Yq11.223

Cellular Component: nucleus

Molecular Function: mRNA binding; nucleotide binding; protein binding

Biological Process: mRNA processing; regulation of alternative nuclear mRNA splicing, via spliceosome; RNA splicing

Disease: Spermatogenic Failure, Y-linked, 2