Rabbit RBMXL2 Polyclonal Antibody | anti-RBMXL2 antibody

RBMXL2 antibody - middle region

Cat. Num. AAA3205467

• Gene Names: RBMXL2; HNRPGT; HNRNPGT; HNRNPG-T
• Reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
• Applications: Western Blot
• Purity: Affinity Purified
• Synonyms: RBMXL2; Polyclonal Antibody; RBMXL2 antibody - middle region; anti-RBMXL2 antibody

• Host: Rabbit
• Reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
• Clonality: Polyclonal
• Purity/Purification: Affinity Purified
• Form/Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Sequence: Synthetic peptide located within the following region: SSRDGYSSRDYREPRGFAPSPGEYTHRDYGHSSVRDDCPLRGYSDRDGYG
• Sequence Length: 392

• Applicable Applications for anti-RBMXL2 antibody: Western Blot (WB)
• Homology: Cow: 85%; Dog: 77%; Guinea Pig: 77%; Horse: 77%; Human: 100%; Mouse: 77%; Rabbit: 85%; Rat: 85%
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RBMXL2
• Preparation and Storage: For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(WB Suggested Anti-RBMXL2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 293T cell lysateRBMXL2 is supported by BioGPS gene expression data to be expressed in HEK293T)

Related Product Information for anti-RBMXL2 antibody

This is a rabbit polyclonal antibody against RBMXL2. It was validated on Western Blot using a cell lysate as a positive control.

Target Description: The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. RBMXL2 has two RRM domains that bind RNAs. RBMXL2 has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2215 AC100875.3 67063-69277 c

Product Categories/Family for anti-RBMXL2 antibody

Polyclonal; RNA Binding Proteins; Chromatin & Nuclear Signaling; E3 & Ubiquitin; DNA/RNA/Protein Interactions

NCBI and Uniprot Product Information

• NCBI GI #: 153252068
• NCBI GeneID: 27288
• NCBI Accession #: NP_055284
• NCBI GenBank Nucleotide #: NM_014469
• UniProt Accession #: O75526
• Molecular Weight: 43kDa
• NCBI Official Full Name: RNA-binding motif protein, X-linked-like-2
• NCBI Official Synonym Full Names: RBMX like 2
• NCBI Official Symbol: RBMXL2
• NCBI Official Synonym Symbols: HNRPGT; HNRNPGT; HNRNPG-T
• NCBI Protein Information: RNA-binding motif protein, X-linked-like-2
• UniProt Protein Name: RNA-binding motif protein, X-linked-like-2
• Protein Family: RNA-binding motif protein
• UniProt Gene Name: RBMXL2
• UniProt Synonym Gene Names: HNRNPGT; hnRNP G-T
• UniProt Entry Name: RMXL2_HUMAN

NCBI Description

This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. [provided by RefSeq, Jul 2008]