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Western Blot (WB) (Western BlotPositive WB detected in:Raji whole cell lysate,NIH/3T3 whole cell lysate,HL-60 whole cell lysate,Mouse skeletal muscle tissueAll lanes: RBM22 antibody at 2.7ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 47,42 kDaObserved band size: 47 kDa)

Rabbit anti-Human RBM22 Polyclonal Antibody | anti-RBM22 antibody

RBM22 Antibody

Gene Names
RBM22; Cwc2; ZC3H16; fSAP47
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
>95%,Protein G purified
Synonyms
RBM22; Polyclonal Antibody; RBM22 Antibody; Pre-mRNA-splicing factor RBM22; RNA-binding motif protein 22; Zinc finger CCCH domain-containing protein 16; ZC3H16; 199G4; anti-RBM22 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Sequence Length
420
Applicable Applications for anti-RBM22 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen
Recombinant human Pre-mRNA-splicing factor RBM22 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-132056 / sc-132057 / sc-132058 / sc-102074
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Western Blot (WB)

(Western BlotPositive WB detected in:Raji whole cell lysate,NIH/3T3 whole cell lysate,HL-60 whole cell lysate,Mouse skeletal muscle tissueAll lanes: RBM22 antibody at 2.7ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 47,42 kDaObserved band size: 47 kDa)

Western Blot (WB) (Western BlotPositive WB detected in:Raji whole cell lysate,NIH/3T3 whole cell lysate,HL-60 whole cell lysate,Mouse skeletal muscle tissueAll lanes: RBM22 antibody at 2.7ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 47,42 kDaObserved band size: 47 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human glioma cancer using MBS7000347 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human glioma cancer using MBS7000347 at dilution of 1:100)
Related Product Information for anti-RBM22 antibody
Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,152 Da
NCBI Official Full Name
pre-mRNA-splicing factor RBM22
NCBI Official Synonym Full Names
RNA binding motif protein 22
NCBI Official Symbol
RBM22
NCBI Official Synonym Symbols
Cwc2; ZC3H16; fSAP47
NCBI Protein Information
pre-mRNA-splicing factor RBM22
UniProt Protein Name
Pre-mRNA-splicing factor RBM22
Protein Family
UniProt Gene Name
RBM22
UniProt Synonym Gene Names
ZC3H16
UniProt Entry Name
RBM22_HUMAN

NCBI Description

This gene encodes an RNA binding protein. The encoded protein may play a role in cell division and may be involved in pre-mRNA splicing. Related pseudogenes exist on chromosomes 6, 7, 9, 13, 16, 18, and X. [provided by RefSeq, Mar 2009]

Uniprot Description

RBM22: Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses. Belongs to the SLT11 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; RNA processing; RNA splicing; Spliceosome

Chromosomal Location of Human Ortholog: 5q33.1

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: calcium-dependent protein binding; metal ion binding; nucleocytoplasmic transporter activity; nucleotide binding; protein binding; U6 snRNA binding

Biological Process: nuclear mRNA cis splicing, via U2-type spliceosome; nuclear mRNA splicing, via spliceosome; positive regulation of RNA splicing; protein import into nucleus, translocation; spliceosomal snRNP biogenesis

Research Articles on RBM22

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Product Notes

The RBM22 rbm22 (Catalog #AAA7000347) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RBM22 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RBM22 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the RBM22 rbm22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RBM22, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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