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Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 861214(RBFOX1 Antibody) at dilution 1/20. (Original magnification: ×200))

Rabbit anti-Human, Mouse RBFOX1 Polyclonal Antibody | anti-RBFOX1 antibody

RBFOX1 Rabbit pAb

Gene Names
RBFOX1; 2BP1; FOX1; A2BP1; FOX-1; HRNBP1
Reactivity
Human, Mouse
Applications
ELISA, Immunohistochemistry
Purity
Affinity purified
Synonyms
RBFOX1; Polyclonal Antibody; RBFOX1 Rabbit pAb; RNA binding protein; fox-1 homolog (C. elegans) 1; 2BP1; FOX1; A2BP1; FOX-1; HRNBP1; anti-RBFOX1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Predominantly expressed in muscle and brain. Gene expression databases
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-RBFOX1 antibody
ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
ELISA: 1:1000-1:2000
IHC: 1:10-1:50
Immunogen
Synthetic peptide of human RBFOX1
Conjugation
Unconjugated
Molecular Function
RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.
Modification
Unmodified
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 861214(RBFOX1 Antibody) at dilution 1/20. (Original magnification: ×200))

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 861214(RBFOX1 Antibody) at dilution 1/20. (Original magnification: ×200))
Related Product Information for anti-RBFOX1 antibody
Ca2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-RBFOX1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,402 Da
NCBI Official Full Name
RNA binding protein fox-1 homolog 1 isoform 4
NCBI Official Synonym Full Names
RNA binding protein, fox-1 homolog (C. elegans) 1
NCBI Official Symbol
RBFOX1
NCBI Official Synonym Symbols
2BP1; FOX1; A2BP1; FOX-1; HRNBP1
NCBI Protein Information
RNA binding protein fox-1 homolog 1
UniProt Protein Name
RNA binding protein fox-1 homolog 1
Protein Family
UniProt Gene Name
RBFOX1
UniProt Synonym Gene Names
A2BP; A2BP1; FOX1; HRNBP1
UniProt Entry Name
RFOX1_HUMAN

NCBI Description

The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Uniprot Description

RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.

Research Articles on RBFOX1

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Product Notes

The RBFOX1 rbfox1 (Catalog #AAA4758371) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RBFOX1 Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RBFOX1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P). ELISA: 1:1000-1:2000 IHC: 1:10-1:50. Researchers should empirically determine the suitability of the RBFOX1 rbfox1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RBFOX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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