Western Blot (WB)
(Western blot analysis of RASSF7 expression in Jurkat cell lysate, The lane on the left is treated with the antigen-specific peptide.)
Rabbit anti-Human, Mouse RASSF7 Polyclonal Antibody | anti-RASSF7 antibody
RASSF7 Antibody
Gene Names
RASSF7; HRC1; HRAS1; C11orf13
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
RASSF7; Polyclonal Antibody; RASSF7 Antibody; C11orf13; Chromosome 11 open reading frame 13; HRAS1; HRAS1 related cluster 1; HRAS1 related cluster protein 1; HRAS1-related cluster protein 1; HRC1; MGC126069; MGC126070; Ras association (RalGDS/AF 6) domain family (N terminal) member 7; Ras association (RalGDS/AF 6) domain family 7; Ras association domain containing protein 7; Ras association domain-containing protein 7; RASF7_HUMAN; RASSF 7; anti-RASSF7 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
RASSF7 antibody detects endogenous levels of total RASSF7
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
337
Applicable Applications for anti-RASSF7 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide
Subcellular Location
Cytoskeleton
Predicted Cross Reactivity
Horse
Similarity
Horse (80%)
Conjugation
Unconjugated
Western Blot (WB)
(Western blot analysis of RASSF7 expression in Jurkat cell lysate, The lane on the left is treated with the antigen-specific peptide.)
Western Blot (WB)
(Western blot analysis of RASSF7 expression in Jurkat cell lysate, The lane on the left is treated with the antigen-specific peptide.)
Related Product Information for anti-RASSF7 antibody
Function: Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.
Subunit Structure: Interacts with MAP2K7 and GTP-bound NRAS.
Post-translational Modifications: Polyubiquitinated and degraded by the proteasome upon prolonged stress stimuli.
Subunit Structure: Interacts with MAP2K7 and GTP-bound NRAS.
Post-translational Modifications: Polyubiquitinated and degraded by the proteasome upon prolonged stress stimuli.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 40 kDa
Predicted: 40 kDa
Predicted: 40 kDa
NCBI Official Full Name
ras association domain-containing protein 7 isoform 2
NCBI Official Synonym Full Names
Ras association domain family member 7
NCBI Official Symbol
RASSF7
NCBI Official Synonym Symbols
HRC1; HRAS1; C11orf13
NCBI Protein Information
ras association domain-containing protein 7
UniProt Protein Name
Ras association domain-containing protein 7
Protein Family
UniProt Gene Name
RASSF7
UniProt Synonym Gene Names
C11orf13; HRC1
Uniprot Description
Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.
Research Articles on RASSF7
Similar Products
Product Notes
The RASSF7 rassf7 (Catalog #AAA9603768) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RASSF7 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RASSF7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the RASSF7 rassf7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RASSF7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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