Rabbit anti-Human RAPGEF6 Polyclonal Antibody | anti-RAPGEF6 antibody
RAPGEF6 Antibody
Gene Names
RAPGEF6; RAGEF2; PDZGEF2; KIA001LB; PDZ-GEF2; RA-GEF-2
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
RAPGEF6; Polyclonal Antibody; RAPGEF6 Antibody; DKFZp667N084; DKFZp686I15116; KIA001LB; PDZ domain containing guanine nucleotide exchange factor (GEF) 2; PDZ domain containing guanine nucleotide exchange factor 2; PDZ domain containing guanine nucleotide exchange factor I; PDZ domain-containing guanine nucleotide exchange factor 2; PDZ GEF 2; PDZ GEF2; PDZ-GEF2; PDZGEF 2; PDZGEF2; RA GEF 2; RA GEF2; RA-GEF-2; RAGEF 2; Rap guanine nucleotide exchange factor (GEF) 6; Rap guanine nucleotide exchange factor 2; Rap guanine nucleotide exchange factor 6; RPGF6_HUMAN; anti-RAPGEF6 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
RAPGEF6 Antibody detects endogenous levels of RAPGEF6.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-RAPGEF6 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human RAPGEF6.
Conjugation
Unconjugated
Subunit Structure
Interacts with the second PDZ domain of human PTP1e.
Tissue Specificity
Isoform 3 has highest expression levels in the brain, heart, liver, lung and placenta and is barely detectable in skeletal muscle, kidney and pancreas.
Function
Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.
Note
Upon binding to M-Ras, it translocates to the plasma membrane.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-RAPGEF6 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
179,423 Da
NCBI Official Full Name
rap guanine nucleotide exchange factor 6 isoform 1
NCBI Official Synonym Full Names
Rap guanine nucleotide exchange factor (GEF) 6
NCBI Official Symbol
RAPGEF6
NCBI Official Synonym Symbols
RAGEF2; PDZGEF2; KIA001LB; PDZ-GEF2; RA-GEF-2
NCBI Protein Information
rap guanine nucleotide exchange factor 6; PDZ domain-containing guanine nucleotide exchange factor 2; PDZ domain-containing guanine nucleotide exchange factor I; PDZ domain containing guanine nucleotide exchange factor (GEF) 2
UniProt Protein Name
Rap guanine nucleotide exchange factor 6
Protein Family
UniProt Gene Name
RAPGEF6
UniProt Synonym Gene Names
PDZGEF2; PDZ-GEF2
UniProt Entry Name
RPGF6_HUMAN
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Product Notes
The RAPGEF6 rapgef6 (Catalog #AAA9631232) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAPGEF6 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RAPGEF6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the RAPGEF6 rapgef6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAPGEF6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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