Immunohistochemistry (IHC)
((3ug/ml) staining of paraffin embedded human tonsil. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.)
Goat RANBPM/RANBP9 Polyclonal Antibody | anti-RANBP9 antibody
Goat anti-RANBPM/RANBP9 Antibody
Immunohistochemistry: In paraffin embedded human tonsil, stains nuclei in epithelial cells of tonsillar criptae. Recommended concentration, 3ug/ml.
Western Blot: Preliminary experiments gave no signal but low background in whole cell Hela lysates at up to 1ug/ml.
Immunocytochemistry: Anonymous customer reported successful use on HeLa.
Immunohistochemistry (IHC)
((3ug/ml) staining of paraffin embedded human tonsil. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.)
Immunohistochemistry (IHC)
((3ug/ml) staining of paraffin embedded human tonsil. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11. [provided by RefSeq, Jul 2008]
Uniprot Description
RANBP9: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA. Belongs to the RANBP9/10 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold; GAPs; GAPs, Ras; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 6p23
Cellular Component: cytoplasm; cytosol; microtubule associated complex; nucleus; plasma membrane
Molecular Function: enzyme binding; protein binding; Ran GTPase binding
Biological Process: axon guidance; microtubule nucleation; protein complex assembly
Research Articles on RANBP9
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Product Notes
The RANBP9 ranbp9 (Catalog #AAA420081) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-RANBPM/RANBP9 Antibody reacts with Tested: Human; Expected from sequence similarity: Human, Mouse, Dog, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's RANBPM/RANBP9 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Immunohistochemistry (IHC), Immunocytochemistry (ICC). Peptide ELISA: Antibody detection limit dilution 1: 16000. Immunohistochemistry: In paraffin embedded human tonsil, stains nuclei in epithelial cells of tonsillar criptae. Recommended concentration, 3ug/ml. Western Blot: Preliminary experiments gave no signal but low background in whole cell Hela lysates at up to 1ug/ml. Immunocytochemistry: Anonymous customer reported successful use on HeLa. Researchers should empirically determine the suitability of the RANBP9 ranbp9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: GSCAFATVED YLH. It is sometimes possible for the material contained within the vial of "RANBPM/RANBP9, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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