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Immunohistochemistry (IHC) (Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit RAIG2 / GPRC5B Polyclonal Antibody | anti-RAIG2 antibody

Rabbit Polyclonal to Human RAIG2 / GPRC5B

Gene Names
GPRC5B; RAIG2; RAIG-2
Reactivity
Gibbon, Bovine, Dog, Gorilla, Horse, Human, Monkey, Mouse, Orangutan, Rabbit, Rat
Predicted Reactivity: Chicken (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
RAIG2 / GPRC5B; Polyclonal Antibody; Rabbit Polyclonal to Human RAIG2 / GPRC5B; Anti-RAIG2 / GPRC5B Antibody (N-Terminus) IHC-plus; GPRC5B; A-69G12.1; RAIG2; RAIG-2; Human RAIG2; anti-RAIG2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Gibbon, Bovine, Dog, Gorilla, Horse, Human, Monkey, Mouse, Orangutan, Rabbit, Rat
Predicted Reactivity: Chicken (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human GPRC5B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
403
Applicable Applications for anti-RAIG2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (5 - 10 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 18 amino acid peptide from N-terminal extracellular domain of human GPRC5B.
Immunogen Type
Synthetic peptide
Immunogen
RAIG2 / GPRC5B antibody was raised against synthetic 18 amino acid peptide from N-terminal extracellular domain of human GPRC5B. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Horse, Rabbit, Opossum (100%); Turkey, Chicken (94%).
Antigen Modification
N-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-RAIG2 antibody
GPRC5B is an Orphan-C GPCR induced by retinoids. GPRC5B shows some homologies to the metabotropic glutamate receptor-like family of GPCRs; however, the GPRC5B protein has a short N-terminal domain compared to other family C members.
Product Categories/Family for anti-RAIG2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,933 Da
NCBI Official Full Name
G-protein coupled receptor family C group 5 member B
NCBI Official Synonym Full Names
G protein-coupled receptor, class C, group 5, member B
NCBI Official Symbol
GPRC5B
NCBI Official Synonym Symbols
RAIG2; RAIG-2
NCBI Protein Information
G-protein coupled receptor family C group 5 member B; A-69G12.1; retinoic acid-induced gene 2 protein; retinoic acid responsive gene protein; G protein-coupled receptor, family C, group 1, member B; G protein-coupled receptor, family C, group 5, member B
UniProt Protein Name
G-protein coupled receptor family C group 5 member B
UniProt Gene Name
GPRC5B
UniProt Synonym Gene Names
RAIG2; RAIG-2
UniProt Entry Name
GPC5B_HUMAN

NCBI Description

The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. [provided by RefSeq, Jul 2008]

Uniprot Description

GPRC5B: Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Belongs to the G-protein coupled receptor 3 family.

Protein type: GPCR, family 3; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16p12

Cellular Component: extracellular space; cell surface; cytoplasmic vesicle membrane; intracellular membrane-bound organelle; plasma membrane; integral to membrane; nucleolus; nucleus; lipid raft

Molecular Function: G-protein coupled receptor activity; G-protein-coupled receptor binding; protein kinase activator activity; protein kinase binding

Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; locomotory behavior; positive regulation of neuron differentiation; glucose homeostasis; positive regulation of inflammatory response

Research Articles on RAIG2

Similar Products

Product Notes

The RAIG2 gprc5b (Catalog #AAA244451) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human RAIG2 / GPRC5B reacts with Gibbon, Bovine, Dog, Gorilla, Horse, Human, Monkey, Mouse, Orangutan, Rabbit, Rat Predicted Reactivity: Chicken (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's RAIG2 / GPRC5B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (5 - 10 ug/ml). Researchers should empirically determine the suitability of the RAIG2 gprc5b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAIG2 / GPRC5B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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