Western Blot (WB)
(All lanes : Anti-Rabphilin 3A Antibody at 1:1000 dilutionLane 1: human brain lysateLane 2: Hela whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution.Predicted band size : 77 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit anti-Human Rabphilin 3A Polyclonal Antibody | anti-RPH3A antibody
Rabphilin 3A Antibody
Western Blot (WB)
(All lanes : Anti-Rabphilin 3A Antibody at 1:1000 dilutionLane 1: human brain lysateLane 2: Hela whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution.Predicted band size : 77 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(All lanes : Anti-Rabphilin 3A Antibody at 1:1000 dilutionLane 1: human brain lysateLane 2: Hela whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution.Predicted band size : 77 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
NCBI and Uniprot Product Information
NCBI Description
Exocytosis of neurotransmitters and hormones is fundamental to synaptic neurotransmission and cell-cell communication. RAB3A (MIM 179390) is a small G protein that is thought to act at late stages of exocytosis, and RPH3A is a RAB3A effector (Lin et al., 2007 [PubMed 17149709]).[supplied by OMIM, Jul 2008]
Uniprot Description
rabphilin 3A: Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 12q24.13
Cellular Component: Golgi apparatus; synaptic vesicle; neuron projection; extrinsic to membrane; protein complex; synaptic vesicle membrane; plasma membrane; synapse; cytosol; cell junction; secretory granule
Molecular Function: phosphatidylinositol-4,5-bisphosphate binding; selenium binding; protein binding; clathrin binding; syntaxin binding; zinc ion binding; calcium-dependent phospholipid binding; protein complex binding; calcium ion binding; phosphate binding; Rab GTPase binding
Biological Process: intracellular protein transport; synaptic vesicle exocytosis; calcium ion-dependent exocytosis of neurotransmitter; brain development; regulation of calcium ion-dependent exocytosis
Research Articles on RPH3A
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Product Notes
The RPH3A rph3a (Catalog #AAA9216014) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabphilin 3A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Rabphilin 3A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB ~~1:1000. Researchers should empirically determine the suitability of the RPH3A rph3a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Rabphilin 3A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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