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Western Blot (WB) (Western blot analysis of RAB40AL Antibdy (N-term) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in ZR-75-1 cell line lysate. RAB40AL Antibdy (N-term) (arrow) was detected using the purified Pab.)

Rabbit anti-Human RAB40AL Polyclonal Antibody | anti-RAB40AL antibody

RAB40AL Antibody (N-term)

Gene Names
RAB40AL; RAR2; RLGP; MRXSMP
Reactivity
Human
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
RAB40AL; Polyclonal Antibody; RAB40AL Antibody (N-term); Ras-related protein Rab-40A-like; Ras-like GTPase; RLGP; anti-RAB40AL antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This RAB40AL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human RAB40AL.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.45 (varies by lot)
Sequence Positions
7-36
Sequence Length
278
Applicable Applications for anti-RAB40AL antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of RAB40AL Antibdy (N-term) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in ZR-75-1 cell line lysate. RAB40AL Antibdy (N-term) (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of RAB40AL Antibdy (N-term) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in ZR-75-1 cell line lysate. RAB40AL Antibdy (N-term) (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(RAB40AL Antibdy (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RAB40AL Antibdy (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (RAB40AL Antibdy (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RAB40AL Antibdy (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-RAB40AL antibody
This gene encodes a member of the Rab40 subfamily of Rab small GTP-binding proteins that contains a C-terminal suppressors of cytokine signaling box. Disruptions in this gene are associated with Duchenne muscular dystrophy.
References
Saito-Ohara, F., et al. Am. J. Hum. Genet. 71(3):637-645(2002) Kile, B.T., et al. Trends Biochem. Sci. 27(5):235-241(2002)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
31239
NCBI Official Full Name
ras-related protein Rab-40A-like
NCBI Official Synonym Full Names
RAB40A, member RAS oncogene family-like
NCBI Official Symbol
RAB40AL
NCBI Official Synonym Symbols
RAR2; RLGP; MRXSMP
NCBI Protein Information
ras-related protein Rab-40A-like
UniProt Protein Name
Ras-related protein Rab-40A-like
Protein Family
UniProt Gene Name
RAB40AL
UniProt Synonym Gene Names
RLGP
UniProt Entry Name
RB40L_HUMAN

NCBI Description

This gene encodes a member of the Rab40 subfamily of Rab small GTP-binding proteins that contains a C-terminal suppressors of cytokine signaling box. Disruptions in this gene are associated with Duchenne muscular dystrophy. [provided by RefSeq, Apr 2010]

Uniprot Description

RAB40AL: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein; G protein, monomeric; Ubiquitin conjugating system; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: Xq22.2

Cellular Component: mitochondrion; cytoplasm; plasma membrane; endosome membrane

Molecular Function: GTPase activity; GDP binding; GTP binding

Biological Process: regulation of exocytosis; intracellular protein transport; protein secretion; protein ubiquitination; Rab protein signal transduction; vesicle docking during exocytosis

Disease: Mental Retardation, X-linked, Syndromic, Martin-probst Type

Research Articles on RAB40AL

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Product Notes

The RAB40AL rab40al (Catalog #AAA9208783) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 7-36. The RAB40AL Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RAB40AL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the RAB40AL rab40al for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAB40AL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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