Rabbit anti-Human RAB34 Polyclonal Antibody | anti-RAB34 antibody

RAB34 Antibody

Cat. Num. AAA9216333

• Gene Names: RAB34; RAH; RAB39
• Reactivity: Human
• Applications: Western Blot
• Synonyms: RAB34; Polyclonal Antibody; RAB34 Antibody; Purified Rabbit Polyclonal Antibody (Pab); Ras-related protein Rab-34; Ras-related protein Rab-39; Ras-related protein Rah; RAB39; RAH; anti-RAB34 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Form/Format: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
• Sequence Length: 251

• Applicable Applications for anti-RAB34 antibody: Western Blot (WB)
• Application Notes: WB ~~1:1000
• Antigen Source: Human
• Antigen Type: A Synthesized Peptide
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Anti-RAB34 Antibody at 1:1000 dilution + Hela whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution.Predicted band size : 29 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Related Product Information for anti-RAB34 antibody

Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.

Product Categories/Family for anti-RAB34 antibody

Immunology; Signal Transduction

References

Hong W.,et al.Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases. Stanchi F.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases. Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Zody M.C.,et al.Nature 440:1045-1049(2006).

NCBI and Uniprot Product Information

• NCBI GI #: 222144317
• NCBI GeneID: 83871
• NCBI Accession #: NP_001138414.1
• NCBI GenBank Nucleotide #: NM_001144942.1
• UniProt Accession #: Q9BZG1; Q5BJE6; Q8NCJ8; Q96AR4; B4E3A0; E9PEJ9
• Molecular Weight: 29044
• NCBI Official Full Name: ras-related protein Rab-34 isoform 4
• NCBI Official Synonym Full Names: RAB34, member RAS oncogene family
• NCBI Official Symbol: RAB34
• NCBI Official Synonym Symbols: RAH; RAB39
• NCBI Protein Information: ras-related protein Rab-34
• UniProt Protein Name: Ras-related protein Rab-34
• Protein Family: Ras-related protein
• UniProt Gene Name: RAB34
• UniProt Synonym Gene Names: RAB39; RAH
• UniProt Entry Name: RAB34_HUMAN

NCBI Description

This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. This gene overlaps and shares exon structure with the nine-amino acid residue-repeats (NARR) gene, which encodes a functionally distinct nucleolar protein from a different reading frame. [provided by RefSeq, Jan 2012]

Uniprot Description

RAB34: Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region. Belongs to the small GTPase superfamily. Rab family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleolus; G protein, monomeric, Rab; G protein, monomeric

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: Golgi apparatus; phagocytic vesicle membrane; Golgi cisterna; Golgi stack; perinuclear region of cytoplasm; phagocytic vesicle; vesicle

Molecular Function: GTPase activity; protein binding; GTP binding; Ral GTPase binding

Biological Process: antigen processing and presentation; lysosome localization; Golgi to plasma membrane protein transport; Rab protein signal transduction