Western Blot (WB)
((0.1 ug/ml) staining of Mouse Eye lyaste (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat RAB23 Polyclonal Antibody | anti-RAB23 antibody
Goat anti-RAB23 Antibody
Western Blot: Approx 30kDa band observed in Mouse Eye lysates (calculated MW of 26.7kDa according to Human NP_057361.3 and 26.8kDa according to Mouse NP_033025.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 1-3ug/ml. Recommended concentration: 1-3ug/ml.
Western Blot (WB)
((0.1 ug/ml) staining of Mouse Eye lyaste (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((0.1 ug/ml) staining of Mouse Eye lyaste (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Uniprot Description
RAB23: Defects in RAB23 are the cause of acrocephalopolysyndactyly type 2 (ACPS2). A syndrome characterized by craniosynostosis, polysyndactyly, obesity, and cardiac defects. Belongs to the small GTPase superfamily. Rab family.
Protein type: G protein, monomeric, Rab; G protein, monomeric; G protein
Chromosomal Location of Human Ortholog: 6p11
Cellular Component: autophagic vacuole; cytoplasm; endosome membrane; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane
Molecular Function: GTP binding; GTPase activity; protein binding
Biological Process: autophagic vacuole formation; cellular defense response; cilium biogenesis; intracellular protein transport; metabolic process; negative regulation of transcription factor import into nucleus; nucleocytoplasmic transport; small GTPase mediated signal transduction
Disease: Carpenter Syndrome 1
Research Articles on RAB23
Similar Products
Product Notes
The RAB23 rab23 (Catalog #AAA421987) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-RAB23 Antibody reacts with Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's RAB23 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 64000. Western Blot: Approx 30kDa band observed in Mouse Eye lysates (calculated MW of 26.7kDa according to Human NP_057361.3 and 26.8kDa according to Mouse NP_033025.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 1-3ug/ml. Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the RAB23 rab23 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: PNKQRTKKNR NP. It is sometimes possible for the material contained within the vial of "RAB23, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
