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Rabbit R-Ras Polyclonal Antibody | anti-R-Ras antibody

R-Ras (Phospho-Tyr66) Polyclonal Conjugated Antibody

Reactivity
Human, Mouse, Rat
Applications
Most Applications
Synonyms
R-Ras; Polyclonal Antibody; R-Ras (Phospho-Tyr66) Polyclonal Conjugated Antibody; R-Ras (Phospho-Tyr66) Conjugated Antibody; RRAS; Oncogene RRAS; R-ras; Ras-related protein R-Ras2; p23; Ras-related protein R-Ras; anti-R-Ras antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
R-Ras (Phospho-Tyr66) antibody detects endogenous levels of R-Ras only when phosphorylated at Tyr66
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Applicable Applications for anti-R-Ras antibody
Most Applications
Application Notes
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
Immunogen
A synthesized peptide derived from human R-Ras (Phospho-Tyr66)
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Preparation and Storage
Store at 4 degree C for 6 months.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,480 Da
NCBI Official Full Name
ras-related protein R-Ras
NCBI Official Synonym Full Names
related RAS viral (r-ras) oncogene homolog
NCBI Official Symbol
RRAS
NCBI Protein Information
ras-related protein R-Ras; Oncogene RRAS; p23
UniProt Protein Name
Ras-related protein R-Ras
UniProt Gene Name
RRAS
UniProt Entry Name
RRAS_HUMAN

NCBI Description

The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq, Jul 2015]

Uniprot Description

RRas: a small G protein of the Ras family. Promotes focal adhesion formation by signaling to FAK and p130(Cas). Promotes tumor growth of cervical epithelial cells and increases their migration potential over collagen through a pathway that involves PI 3-K.

Protein type: G protein, monomeric, Ras; G protein; Motility/polarity/chemotaxis; G protein, monomeric

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: focal adhesion; plasma membrane

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; protein complex binding

Biological Process: axon guidance; synaptic transmission; positive regulation of angiogenesis; metabolic process; Ras protein signal transduction; leukocyte differentiation; regulation of protein kinase B signaling cascade; negative regulation of cell migration

Research Articles on R-Ras

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Product Notes

The R-Ras rras (Catalog #AAA9438129) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The R-Ras (Phospho-Tyr66) Polyclonal Conjugated Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's R-Ras can be used in a range of immunoassay formats including, but not limited to, Most Applications. Suggested Dilution: AF350 conjugated: most applications: 1:50-1:250 AF405 conjugated: most applications: 1:50-1:250 AF488 conjugated: most applications: 1:50-1:250 AF555 conjugated: most applications: 1:50-1:250 AF594 conjugated: most applications: 1:50-1:250 AF647 conjugated: most applications: 1:50-1:250 AF680 conjugated: most applications: 1:50-1:250 AF750 conjugated: most applications: 1:50-1:250 Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000. Researchers should empirically determine the suitability of the R-Ras rras for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "R-Ras, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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