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Goat anti-Human PTX3 Polyclonal Antibody

Anti-PTX3 (Pentraxin-related Protein PTX3, Pentaxin-related Protein PTX3, Tumor Necrosis Factor alpha-induced Protein 5, TNF alpha-induced Protein 5, Tumor Necrosis Factor-inducible Gene 14 Protein, TSG-14, TNFAIP5, TSG14)

Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
PTX3; Polyclonal Antibody; Anti-PTX3 (Pentraxin-related Protein PTX3; Pentaxin-related Protein PTX3; Tumor Necrosis Factor alpha-induced Protein 5; TNF alpha-induced Protein 5; Tumor Necrosis Factor-inducible Gene 14 Protein; TSG-14; TNFAIP5; TSG14); Pentraxin-related Protein PTX3; TSG14; anti-PTX3 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human PTX3.
Purity/Purification
Affinity Purified
Form/Format
Supplied as a liquid in PBS, 0.1% BSA.
Concentration
~1mg/ml (varies by lot)
Applicable Applications for anti-PTX3 antibody
ELISA; Western Blot; Immunohistochemistry
Application Notes
Suitable for use in Western Blot, Immunohistochemistry, and ELISA.
Recommended Dilutions: Western Blot: 1-3ug/ml (ECL)
ELISA: 0.1-1ug/ml
Immunohistochemistry: 2-10ug/ml
Immunogen
Recombinant corresponding to human PTX3.
Source Information
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Temperature: Blue Ice
Related Product Information for anti-PTX3 antibody
Pentraxins are a family of proteins emerging from genes that are conserved in their carboxy-terminal halves a pentraxin domain and are prototypical acute phase proteins with acquired novel amino-terminal domains. Pentraxins, include C reactive protein (CRP) and Serum Amyloid P component (SAP), which serve as indicators of inflammatory reactions as a result of the exposure of liver cells to cytokines, mainly interleukin-6 (IL-6). PTX3 or TSG14 or long pentraxin (human mature chain 364aa, chromosome 3q25; ~43kD) is structurally related but different form classic pentraxins. PTX3 was clones as an IL-1 inducible gene in endothelial cells, and as TNF-inducible gene in fibroblasts called TSG14. The C-terminal half of PTX3 aligns with CRP and SAP, but the N-terminal half is unique. PTX3 is induced by LPS, IL-1 and TNF-alpha, but not IL-6. During an acute phase response induced by LPS, PTX3 is expressed in many organs (heart, skeletal muscle). PTX3 expression may be indicative of its role in cardiovascular and inflammatory pathology.
Product Categories/Family for anti-PTX3 antibody

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Product Notes

The PTX3 (Catalog #AAA628753) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Anti-PTX3 (Pentraxin-related Protein PTX3, Pentaxin-related Protein PTX3, Tumor Necrosis Factor alpha-induced Protein 5, TNF alpha-induced Protein 5, Tumor Necrosis Factor-inducible Gene 14 Protein, TSG-14, TNFAIP5, TSG14) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTX3 can be used in a range of immunoassay formats including, but not limited to, ELISA; Western Blot; Immunohistochemistry. Suitable for use in Western Blot, Immunohistochemistry, and ELISA. Recommended Dilutions: Western Blot: 1-3ug/ml (ECL) ELISA: 0.1-1ug/ml Immunohistochemistry: 2-10ug/ml. Researchers should empirically determine the suitability of the PTX3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTX3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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