Western Blot (WB)
(Western blot analysis of PTS using HuvEc whole cell lysates)
Rabbit anti-Human PTS Polyclonal Antibody | anti-PTS antibody
PTS Antibody
Gene Names
PTS; PTPS
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
PTS; Polyclonal Antibody; PTS Antibody; 6 pyruvoyl tetrahydrobiopterin synthase; 6 pyruvoyl tetrahydropterin synthase; 6 pyruvoyltetrahydropterin synthase; 6-pyruvoyl tetrahydrobiopterin synthase; EC 4.2.3.12; FLJ97081; OTTHUMP00000235385; PTP synthase; PTPS; PTPS_HUMAN; anti-PTS antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
PTS antibody detects endogenous levels of total PTS
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
145
Applicable Applications for anti-PTS antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human PTS
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of PTS using HuvEc whole cell lysates)
Western Blot (WB)
(Western blot analysis of PTS using HuvEc whole cell lysates)
Related Product Information for anti-PTS antibody
Function: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7, 8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.
Subunit Structure: Homohexamer formed of two homotrimers in a head to head fashion.
Post-translational Modifications: Phosphorylation of Ser-19 is required for maximal enzyme activity.
Similarity: Belongs to the PTPS family.
Subunit Structure: Homohexamer formed of two homotrimers in a head to head fashion.
Post-translational Modifications: Phosphorylation of Ser-19 is required for maximal enzyme activity.
Similarity: Belongs to the PTPS family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 16 kDa
Predicted: 17 kDa
Predicted: 17 kDa
NCBI Official Full Name
6-pyruvoyl tetrahydrobiopterin synthase
NCBI Official Synonym Full Names
6-pyruvoyltetrahydropterin synthase
NCBI Official Symbol
PTS
NCBI Official Synonym Symbols
PTPS
NCBI Protein Information
6-pyruvoyl tetrahydrobiopterin synthase
UniProt Protein Name
6-pyruvoyl tetrahydrobiopterin synthase
Protein Family
UniProt Gene Name
PTS
UniProt Synonym Gene Names
PTP synthase; PTPS
NCBI Description
The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq, Oct 2008]
Uniprot Description
Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.
Research Articles on PTS
Similar Products
Product Notes
The PTS pts (Catalog #AAA9608577) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTS Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTS can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the PTS pts for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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