Western Blot (WB)
(PTPN23 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the PTPN23 antibody detected the PTPN23 protein (arrow).)
Rabbit anti-Human PTPN23 Polyclonal Antibody | anti-PTPN23 antibody
PTPN23, CT (PTPN23, KIAA1471, Tyrosine-protein phosphatase non-receptor type 23, His domain-containing protein tyrosine phosphatase, Protein tyrosine phosphatase TD14) (FITC)
Gene Names
PTPN23; HDPTP; HD-PTP; PTP-TD14
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PTPN23; Polyclonal Antibody; CT (PTPN23; KIAA1471; Tyrosine-protein phosphatase non-receptor type 23; His domain-containing protein tyrosine phosphatase; Protein tyrosine phosphatase TD14) (FITC); Protein tyrosine phosphatase TD14; anti-PTPN23 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Applicable Applications for anti-PTPN23 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
PTPN23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1180-1209 amino acids from the C-terminal region of human PTPN23.
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(PTPN23 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the PTPN23 antibody detected the PTPN23 protein (arrow).)
Western Blot (WB)
(PTPN23 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the PTPN23 antibody detected the PTPN23 protein (arrow).)
Related Product Information for anti-PTPN23 antibody
PTPN23 may act as a negative regulator of Ras-mediated mitogenic activity.
Product Categories/Family for anti-PTPN23 antibody
References
Mariotti, M., et al. Int. J. Biochem. Cell Biol. 41(3):687-693(2009). Mariotti, M., et al. Cancer Lett. 273(1):155-163(2009). Gingras, M.C., et al. PLoS ONE 4 (4), E5105 (2009): Castiglioni, S., et al. Biochem. Biophys. Res. Commun. 364(3):534-539(2007). Matsuoka, S., et al. Science 316(5828):1160-1166(2007).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
178,974 Da
NCBI Official Full Name
tyrosine-protein phosphatase non-receptor type 23
NCBI Official Synonym Full Names
protein tyrosine phosphatase, non-receptor type 23
NCBI Official Symbol
PTPN23
NCBI Official Synonym Symbols
HDPTP; HD-PTP; PTP-TD14
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 23; protein tyrosine phosphatase TD14; His-domain protein tyrosine phosphatase; his domain-containing protein tyrosine phosphatase
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type 23
Protein Family
UniProt Gene Name
PTPN23
UniProt Synonym Gene Names
KIAA1471; HD-PTP; PTP-TD14
UniProt Entry Name
PTN23_HUMAN
Uniprot Description
PTPN23: May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis. Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
Protein type: EC 3.1.3.48; Protein phosphatase, tyrosine (non-receptor); Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 3p21.3
Cellular Component: nucleoplasm; cytoplasmic membrane-bound vesicle; cytoplasm; early endosome; nucleus; endosome
Molecular Function: protein binding; protein tyrosine phosphatase activity; protein kinase binding
Biological Process: protein transport; ubiquitin-dependent protein catabolic process via the multivesicular body pathway
Similar Products
Product Notes
The PTPN23 ptpn23 (Catalog #AAA6339011) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTPN23, CT (PTPN23, KIAA1471, Tyrosine-protein phosphatase non-receptor type 23, His domain-containing protein tyrosine phosphatase, Protein tyrosine phosphatase TD14) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTPN23 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PTPN23 ptpn23 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTPN23, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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