Western Blot (WB)
(PTPN18 Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PTPN18 antibody detected the PTPN18 protein (arrow).)
Rabbit PTPN18 Polyclonal Antibody | anti-PTPN18 antibody
PTPN18 Antibody (C-term)
Western Blot (WB)
(PTPN18 Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PTPN18 antibody detected the PTPN18 protein (arrow).)
Western Blot (WB)
(PTPN18 Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PTPN18 antibody detected the PTPN18 protein (arrow).)
Western Blot (WB)
(Western blot analysis of PTPN18 (arrow) using rabbit polyclonal PTPN18 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PTPN18 gene.)
Western Blot (WB)
(Western blot analysis of PTPN18 (arrow) using rabbit polyclonal PTPN18 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PTPN18 gene.)
protein tyrosine phosphatase (PTP) family. PTPs are known to be
signaling molecules that regulate a variety of cellular processes
including cell growth, differentiation, the mitotic cycle, and
oncogenic transformation. This PTP contains a PEST motif, which
often serves as a protein-protein interaction domain, and may be
related to protein intracellular half-live. This protein can
differentially dephosphorylate autophosphorylated tyrosine kinases
that are overexpressed in tumor tissues, and it appears to regulate
HER2, a member of the epidermal growth factor receptor family of
receptor tyrosine kinases. Two transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq].
Zhang, Y., et al. Mol. Cell Proteomics 4(9):1240-1250(2005)
Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)
Blanchetot, C., et al. Methods 35(1):44-53(2005)
Gandhi, T.K., et al. DNA Res. 12(2):79-89(2005)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Uniprot Description
BDP1: a member of the non-receptor protein tyrosine phosphatase (PTP) family. Contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This gene was found to be expressed in brain, colon tissues, and several different tumor-derived cell lines.
Protein type: EC 3.1.3.48; Motility/polarity/chemotaxis; Protein phosphatase, tyrosine (non-receptor)
Chromosomal Location of Human Ortholog: 2q21.1
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding; non-membrane spanning protein tyrosine phosphatase activity
Biological Process: protein amino acid dephosphorylation
Research Articles on PTPN18
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Product Notes
The PTPN18 ptpn18 (Catalog #AAA9201396) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 430-459. The PTPN18 Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's PTPN18 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the PTPN18 ptpn18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTPN18, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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