Immunohistochemistry (IHC)
(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit PTP1B Polyclonal Antibody | anti-ptpn1 antibody
PTP1B, NT (Tyrosine-protein Phosphatase Non-receptor Type 1, Protein-tyrosine Phosphatase 1B, PTP-1B, PTPN1, PTP1B)
Gene Names
ptpn1; ptp1b; wu:fk54h03
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity PurifiedPurified by immunoaffinity chromatography
Synonyms
PTP1B; Polyclonal Antibody; NT (Tyrosine-protein Phosphatase Non-receptor Type 1; Protein-tyrosine Phosphatase 1B; PTP-1B; PTPN1; PTP1B); Anti -PTP1B; anti-ptpn1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human PTPN1/PTP1B. Species Crossreactivity: Mouse, rat.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography
Purified by immunoaffinity chromatography
Form/Format
Supplied as a liquid in PBS, (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Applicable Applications for anti-ptpn1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA, Western Blot, Immunohistochemistry.
Dilution: ELSA: 1:20,000
Western Blot: 1:500-1:1000
Immunohistochemistry (Paraffin): 10ug/ml
Dilution: ELSA: 1:20,000
Western Blot: 1:500-1:1000
Immunohistochemistry (Paraffin): 10ug/ml
Immunogen
Synthetic peptide corresponding to human PTPN1/PTP1B at N-Terminal.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunohistochemistry (IHC)
(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
Western Blot (WB)
(Western blot analysis of extracts from COS7 cells, treated with UV 30', using PTP1B. The lane on the right is treated with the synthesized peptide.)
Western Blot (WB)
(Western blot analysis of extracts from COS7 cells, treated with UV 30', using PTP1B. The lane on the right is treated with the synthesized peptide.)
Related Product Information for anti-ptpn1 antibody
PTP1B, a NT1 non-receptor protein tyrosine phosphatase, has been shown to regulate insulin signaling, integrin signaling, and leptin signaling. It has been shown that JAK2 and TYK2 are physiological substrates of PTP1B and that the substrate recognition site within theses kinases is similar to the site of dephosphorylation identified within the insulin receptor. The knowledge that mice lacking PTP1B are hypersensitive to insulin and resistant to obesity and that insulin signaling can be enhanced by the inhibition of PTP1B have made PTP1B a potential therapy target against type 2 diabetes and obesity.
Product Categories/Family for anti-ptpn1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Ptp1b protein
NCBI Official Synonym Full Names
protein tyrosine phosphatase, non-receptor type 1
NCBI Official Symbol
ptpn1
NCBI Official Synonym Symbols
ptp1b; wu:fk54h03
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 1; PTP-1B; fk54h03; protein tyrosine phosphatase 1b; protein-tyrosine phosphatase 1B
Protein Family
Similar Products
Product Notes
The ptpn1 (Catalog #AAA6000406) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTP1B, NT (Tyrosine-protein Phosphatase Non-receptor Type 1, Protein-tyrosine Phosphatase 1B, PTP-1B, PTPN1, PTP1B) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PTP1B can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot, Immunohistochemistry. Dilution: ELSA: 1:20,000 Western Blot: 1:500-1:1000 Immunohistochemistry (Paraffin): 10ug/ml. Researchers should empirically determine the suitability of the ptpn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTP1B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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