Western Blot (WB)
(PTGR1 Antibody (Center) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the PTGR1 antibody detected PTGR1 protein (arrow).)
Rabbit anti-Human, Mouse PTGR1 Polyclonal Antibody | anti-PTGR1 antibody
PTGR1, ID (PTGR1, LTB4DH, Prostaglandin reductase 1, 15-oxoprostaglandin 13-reductase, NADP-dependent leukotriene B4 12-hydroxydehydrogenase) (AP)
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Western Blot (WB)
(PTGR1 Antibody (Center) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the PTGR1 antibody detected PTGR1 protein (arrow).)
Western Blot (WB)
(PTGR1 Antibody (Center) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the PTGR1 antibody detected PTGR1 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
Uniprot Description
LTB4DH: Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha. Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4. Belongs to the NADP-dependent oxidoreductase L4BD family.
Protein type: Oxidoreductase; EC 1.3.1.74; EC 1.3.1.48
Chromosomal Location of Human Ortholog: 9q31.3
Cellular Component: cytoplasm
Molecular Function: 15-oxoprostaglandin 13-oxidase activity; zinc ion binding; 2-alkenal reductase activity
Biological Process: response to toxin; cyclooxygenase pathway; arachidonic acid metabolic process; leukotriene metabolic process
Research Articles on PTGR1
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Product Notes
The PTGR1 ptgr1 (Catalog #AAA6338733) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTGR1, ID (PTGR1, LTB4DH, Prostaglandin reductase 1, 15-oxoprostaglandin 13-reductase, NADP-dependent leukotriene B4 12-hydroxydehydrogenase) (AP) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PTGR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PTGR1 ptgr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTGR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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