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Western Blot (WB) ((0.5ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Goat PTCHD1 Polyclonal Antibody | anti-PTCHD1 antibody

Goat anti-PTCHD1 Antibody

Gene Names
PTCHD1; AUTSX4
Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Applications
ELISA, Western Blot
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
PTCHD1; Polyclonal Antibody; Goat anti-PTCHD1 Antibody; patched domain containing 1; FLJ30296; MGC149798; FLJ30296 antibody; MGC149798 antibody; patched domain containing 1 antibody; PTCHD1 antibody; anti-PTCHD1 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
DFQKTSRVSER
Sequence Length
888
Applicable Applications for anti-PTCHD1 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 16000.
Immunogen
Peptide with sequence C-DFQKTSRVSER, from the internal region of the protein sequence according to NP_775766.2.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

Western Blot (WB)

((0.5ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Western Blot (WB) ((0.5ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28,889 Da
NCBI Official Full Name
patched domain-containing protein 1
NCBI Official Synonym Full Names
patched domain containing 1
NCBI Official Symbol
PTCHD1
NCBI Official Synonym Symbols
AUTSX4
NCBI Protein Information
patched domain-containing protein 1
UniProt Protein Name
Patched domain-containing protein 1
UniProt Gene Name
PTCHD1
UniProt Entry Name
PTHD1_HUMAN

NCBI Description

This gene encodes a membrane protein with a patched domain. The encoded protein is similar to Drosophila proteins which act as receptors for the morphogen sonic hedgehog. Deletions in this gene, which is located on the X chromosome, are associated with intellectual disability and autism (PMID: 21091464, PMID: 20844286). [provided by RefSeq, Aug 2011]

Uniprot Description

PTCHD1: a membrane protein with a patched domain. The encoded protein is similar to Drosophila proteins which act as receptors for the morphogen sonic hedgehog. Deletions in this gene, which is located on the X chromosome, are associated with intellectual disability and autism (PMID: 21091464, PMID: 20844286). [provided by RefSeq, Aug 2011]

Protein type: Receptor, misc.; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xp22.11

Cellular Component: integral to membrane; plasma membrane

Molecular Function: hedgehog receptor activity

Biological Process: cognition; smoothened signaling pathway

Disease: Autism, Susceptibility To, X-linked 4

Research Articles on PTCHD1

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Product Notes

The PTCHD1 ptchd1 (Catalog #AAA422510) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-PTCHD1 Antibody reacts with Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's PTCHD1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 16000. Researchers should empirically determine the suitability of the PTCHD1 ptchd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: DFQKTSRVSE R. It is sometimes possible for the material contained within the vial of "PTCHD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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