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Immunohistochemistry (IHC) (Anti-PSCA antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Rabbit anti-Human, Mouse PSCA Polyclonal Antibody | anti-PSCA antibody

Rabbit Polyclonal to Human PSCA

Gene Names
PSCA; PRO232
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
PSCA; Polyclonal Antibody; Rabbit Polyclonal to Human PSCA; Anti-PSCA Antibody (aa41-90) IHC-plus; Prostate stem cell antigen; PRO232; Human PSCA; anti-PSCA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
Human PSCA
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, pH 7.2, 0.05% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
114
Applicable Applications for anti-PSCA antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes
IHC-P (10 ug/ml), WB (1:500 - 1:1000)
Target Species
Human
Immunogen Description
Synthetic peptide, corresponding to amino acids 41-90 of Human PSCA.
Immunogen Type
Synthetic peptide
Immunogen
PSCA antibody was raised against synthetic peptide, corresponding to amino acids 41-90 of Human PSCA.
Antigen Modification
aa41-90
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Anti-PSCA antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC) (Anti-PSCA antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Western Blot (WB)

(Western blot of Prostate Stem Cell Antigen (V71) pAb in extracts from HepG2 cells.)

Western Blot (WB) (Western blot of Prostate Stem Cell Antigen (V71) pAb in extracts from HepG2 cells.)
Related Product Information for anti-PSCA antibody
Prostate stem cell antigen (PSCA) is a cell surface antigen expressed by both androgen-dependent and -independent prostate cancers. In addition to normal prostate, it is also expressed in bladder, colon, esophagus, kidney, stomach and the urinary tract.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
12,912 Da
NCBI Official Full Name
prostate stem cell antigen preproprotein
NCBI Official Synonym Full Names
prostate stem cell antigen
NCBI Official Symbol
PSCA
NCBI Official Synonym Symbols
PRO232
NCBI Protein Information
prostate stem cell antigen
UniProt Protein Name
Prostate stem cell antigen
UniProt Gene Name
PSCA
UniProt Entry Name
PSCA_HUMAN

NCBI Description

This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Uniprot Description

PSCA: May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 8q24.2

Cellular Component: plasma membrane

Research Articles on PSCA

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Product Notes

The PSCA psca (Catalog #AAA248389) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human PSCA reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PSCA can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (10 ug/ml), WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the PSCA psca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PSCA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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