Immunohistochemistry (IHC)
(Anti-STT3A antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Mouse anti-Human STT3A / ITM1 Monoclonal Antibody | anti-STT3A antibody
Mouse Monoclonal [clone 4D4] (IgG1,k) to Human STT3A / ITM1
Usage: Western Blot (Transfected lysate) - positive control transfected 293T cell line. Sandwich ELISA (Recombinant protein).
Immunohistochemistry (IHC)
(Anti-STT3A antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-STT3A antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Western Blot (WB)
(Western blot of ITM1 expression in transfected 293T cell line by ITM1 monoclonal antibody clone 4D4.)
Western Blot (WB)
(Western blot of ITM1 expression in transfected 293T cell line by ITM1 monoclonal antibody clone 4D4.)
ELISA (EIA)
(Detection limit for recombinant GST tagged ITM1 is approximately 1 ng/ml as a capture antibody.)
ELISA (EIA)
(Detection limit for recombinant GST tagged ITM1 is approximately 1 ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
Uniprot Description
ITM1: Catalytic component of oligosaccharyltransferase (OST) oligosaccharyltransferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X- Ser/Thr consensus motif in nascent polypeptide chains. N- glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A. Belongs to the STT3 family.
Protein type: Transferase; Endoplasmic reticulum; EC 2.4.99.18; Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: membrane; endoplasmic reticulum; integral to membrane
Molecular Function: transferase activity; transferase activity, transferring glycosyl groups; dolichyl-diphosphooligosaccharide-protein glycotransferase activity; oligosaccharyl transferase activity
Biological Process: co-translational protein modification; protein amino acid glycosylation; protein amino acid N-linked glycosylation via asparagine
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Product Notes
The STT3A stt3a (Catalog #AAA246356) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 4D4] (IgG1,k) to Human STT3A / ITM1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STT3A / ITM1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA, IHC-P (5 ug/ml), WB Usage: Western Blot (Transfected lysate) - positive control transfected 293T cell line. Sandwich ELISA (Recombinant protein). Researchers should empirically determine the suitability of the STT3A stt3a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STT3A / ITM1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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