Rabbit PRPF40A Polyclonal Antibody | anti-PRPF40A antibody

PRPF40A Polyclonal Antibody

Cat. Num. AAA3007377

• Gene Names: PRPF40A; HYPA; FBP11; FLAF1; FNBP3; HIP10; Prp40; FBP-11; HIP-10; NY-REN-6
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: PRPF40A; Polyclonal Antibody; PRPF40A Polyclonal Antibody; Pre-mRNA-processing factor 40 homolog A; Fas ligand-associated factor 1; Formin-binding protein 11; Formin-binding protein 3; Huntingtin yeast partner A; Huntingtin-interacting protein 10; HIP-10; Huntingtin-interacting protein A; Renal carcinoma antigen NY-REN-6; FBP11; FLAF1; FNBP3; HIP10; HYPA; HSPC225; anti-PRPF40A antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: PRPF40A polyclonal antibody detects endogenous levels of PRPF40A protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 414

• Applicable Applications for anti-PRPF40A antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: Synthetic peptide, corresponding to amino acids 466-511 of Human PRPF40A.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of PRPF40A polyclonal antibody at 1:500 dilutionLane1:Hela whole cell lysate (40ug) Lane2:The Brain tissue lysate of Rat (30ug) Lane3:The Brain tissue lysate of Mouse (30ug))

Related Product Information for anti-PRPF40A antibody

FNBP3, Formin-binding protein 3, is a 957 amino acid protein encoded by the human gene PRPF40A. FNBP3 belongs to the PRPF40 family and contains five FF domains and two WW domains. Nuclear proteins harboring both WW and FF protein interaction modules bind to splicing factors as well as RNA polymerase II and may serve to link transcription with splicing. Through the WW domains, FNBP3 will bind to the Formin proline-rich regions. Also known as Pre-mRNA-processing factor 40 homolog A, FNBP3 binds to WASL/N-WASP (Neuronal Wiskott-Aldrich syndrome protein) complex and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function. FNBP3 is widely expressed in most tissues and is localized to the nuclear speckles.

NCBI and Uniprot Product Information

• NCBI GI #: 116283494
• NCBI GeneID: 55660
• UniProt Accession #: O75400
• Molecular Weight: ~ 108kDa
• NCBI Official Full Name: PRPF40A protein, partial
• NCBI Official Synonym Full Names: pre-mRNA processing factor 40 homolog A
• NCBI Official Symbol: PRPF40A
• NCBI Official Synonym Symbols: HYPA; FBP11; FLAF1; FNBP3; HIP10; Prp40; FBP-11; HIP-10; NY-REN-6
• NCBI Protein Information: pre-mRNA-processing factor 40 homolog A
• UniProt Protein Name: Pre-mRNA-processing factor 40 homolog A
• Protein Family: Pre-mRNA-processing factor
• UniProt Gene Name: PRPF40A
• UniProt Synonym Gene Names: FBP11; FLAF1; FNBP3; HIP10; HYPA; HIP-10

Uniprot Description

Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing.