Goat PrP Polyclonal Antibody | anti-PrP antibody
PrP antibody
Applications
User optimized
Synonyms
PrP; Polyclonal Antibody; PrP antibody; Polyclonal PrP; Anti-PrP; Prion protein; PrP 27-30 N-terminus; Prion; anti-PrP antibody
Host
Goat
Clonality
Polyclonal
Sequence Length
256
Applicable Applications for anti-PrP antibody
User optimized
Biological Significance
Major prion protein (PrP) also known as CD230 (cluster of differentiation 230) is a protein that in humans is encoded by the PRNP gene. The major prion protein is expressed in the brain and several other tissues. Two distinct major conformational forms of PrP have been identified in the nervous system. The usual cellular form is denoted PrPC (for cellular or common form). Another form, PrPSc (for scrapie), has an identical amino acid sequence, but is folded into a different shape or conformation.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-PrP antibody
Affinity purified Goat polyclonal PrP antibody
Product Categories/Family for anti-PrP antibody
NCBI and Uniprot Product Information
Uniprot Description
Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu2+ or ZN2+ for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains ().
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Product Notes
The PrP prnp (Catalog #AAA536411) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PrP can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the PrP prnp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PrP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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